Hypoglycemia – Epidemiology Forecast to 2030

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Hypoglycemia is a condition in which a person’s glucose, or blood sugar, level is lower than normal. It most often, although not exclusively, occurs in patients with drug-treated type 1 (T1D) or type 2 diabetes mellitus (T2D), as glucose-lowering medications can lead to hypoglycemia (Silbert et al., 2018). Symptoms of hypoglycemia include fatigue, fast heartbeat, shakiness, anxiety, and hunger. During a severe hypoglycemic episode, symptoms can escalate to blurred vision, confusion, seizures, or even loss of consciousness. In those without diabetes, causes of hypoglycemia can include excessive alcohol intake, taking certain medications, and hormone deficiencies (Mayo Clinic, 2021).

GlobalData epidemiologists utilized nationally representative and country-specific peer-reviewed journal articles to arrive at a meaningful, in-depth analysis and forecast for the diagnosed incident cases of hypoglycemia. For the 7MM, hypoglycemia cases attributed to T1D, T2D, and all diabetes were segmented by age, sex, and severity. Finally, historical data were evaluated in all 7MM to strengthen the forecast by more accurately capturing changes in incidence throughout the forecast period.

GlobalData epidemiologists forecast that the diagnosed incident cases of hypoglycemia attributed to T1D and T2D in the 7MM will grow by an annual growth rate (AGR) of 0.21% over the next 10 years, from 1,483,850 cases in 2020 to 1,515,114 cases in 2030. Diagnosed incident cases of non-diabetic hypoglycemia will increase from 479,409 cases in 2020 to 489,344 cases in 2030 in the 7MM, at an AGR of 0.21%. These trends mirror changes in the underlying, at-risk populations, such as the rising incidence of T2D, the most common type of diabetes. While hypoglycemia has long been recognized as an inevitable consequence of diabetes therapy, it is being increasingly viewed as a potentially preventable cause of impaired quality of life and mortality.

Scope

The Hypoglycemia Epidemiology Report and Model provide an overview of the risk factors, comorbidities, and global trends of Hypoglycemia in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).

The report includes a 10-year epidemiological forecast for the diagnosed incident cases of hypoglycemia attributed to type 1 and type 2 diabetes. The diagnosed incident cases are segmented by age (0–9 years, and by 10-year age groups for age 10 years up to 80 years and older) and sex. The diagnosed incident cases of hypoglycemia attributed to all diabetes are additionally segmented by severity (non-severe versus severe) and, among severe cases, by hospitalized incident cases. The diagnosed incident cases of hypoglycemia in the non-diabetic and bariatric surgery populations are also forecasted.

The hypoglycemia epidemiology report and model were written and developed by Masters- and PhD-level epidemiologists.

• The Epidemiology Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.

• The Epidemiology Model is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.

Reasons to Buy

The Hypoglycemia Epidemiology series will allow you to:

Develop business strategies by understanding the trends shaping and driving the global hypoglycemia markets.

Quantify patient populations in the global hypoglycemia markets to improve product design, pricing, and launch plans.

Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for hypoglycemia therapeutics in each of the markets covered.

Understand magnitude of the hypoglycemia population by age, sex, and severity.

Table of Contents

| Contents

| List of Tables

| List of Figures

| About GlobalData

1 Hypoglycemia: Executive Summary

1.1 Related Reports

1.2 Upcoming Reports

2 Epidemiology

2.1 Disease Background

2.2 Risk Factors and Comorbidities

2.3 Global and Historical Trends

2.3.1 Diagnosed Incidence of Hypoglycemia Attributed to Type 1 Diabetes

2.3.2 Diagnosed Incidence of Hypoglycemia Attributed to Type 2 Diabetes

2.4 7MM Forecast Methodology

2.4.1 Sources

2.4.2 Sources Not Used

2.4.3 Forecast Assumptions and Methods

2.4.4 Diagnosed Incident Cases of Type 1 Diabetes

2.4.5 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes

2.4.6 Diagnosed Incident Cases of Type 2 Diabetes

2.4.7 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes

2.4.8 Diagnosed Incident Cases of Non-Diabetic Hypoglycemia

2.4.9 Diagnosed Incident Cases of Hypoglycemia in Bariatric Surgery Population

2.5 Epidemiological Forecast for Hypoglycemia (2020–2030)

2.5.1 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes

2.5.2 Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes

2.5.3 Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes

2.5.4 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes by Severity

2.5.5 Hospitalized Severe Incident Cases of Hypoglycemia Attributed to Type 1 Diabetes

2.5.6 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes

2.5.7 Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes

2.5.8 Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes

2.5.9 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes by Severity

2.5.10 Hospitalized Severe Incident Cases of Hypoglycemia Attributed to Type 2 Diabetes

2.5.11 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 and Type 2 Diabetes

2.5.12 Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 and Type 2 Diabetes

2.5.13 Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 and Type 2 Diabetes

2.5.14 Diagnosed Incident Cases of Hypoglycemia Attributed to Type 1 and Type 2 Diabetes by Severity

2.5.15 Hospitalized Severe Incident Cases of Hypoglycemia Attributed to Type 1 and Type 2 Diabetes

2.5.16 Diagnosed Incident Cases of Non-Diabetic Hypoglycemia

2.5.17 Diagnosed Incident Cases of Hypoglycemia in the Bariatric Surgery Population

2.6 Discussion

2.6.1 Epidemiological Forecast Insight

2.6.2 COVID-19 Impact

2.6.3 Limitations of the Analysis

2.6.4 Strengths of the Analysis

3 Appendix

3.1 Bibliography

3.2 About the Authors

3.2.1 Epidemiologist

3.2.2 Reviewers

3.2.3 Global Director of Therapy Analysis and Epidemiology

3.2.4 Global Head and EVP of Healthcare Operations and Strategy

| Contact Us

Table

Table 1: Risk Factors and Comorbidities for Hypoglycemia

Figures

Figure 1: 7MM, Diagnosed Incident Cases of Hypoglycemia Attributed to T1D and T2D, Both Sexes, All Ages, 2020 and 2030

Figure 2: 7MM, Diagnosed Incident Cases of Non-Diabetic Hypoglycemia, Both Sexes, All Ages, 2020 and 2030

Figure 3: 7MM, Diagnosed Incidence of Hypoglycemia Attributed to Type 1 Diabetes, Men and Women, All Ages, 2010–2030 (Cases per 100,000 Population)

Figure 4: 7MM, Diagnosed Incidence of Hypoglycemia Attributed to Type 2 Diabetes, Men and Women, All Ages, 2010–2030 (Cases per 100,000 Population)

Figure 5: Sources Used for Diagnosed Incident Cases of T1D

Figure 6: Sources Used for Diagnosed Incident Cases of T2D

Figure 7: Sources Used for Diagnosed Incident Cases of Non-Severe, Severe, and All Hypoglycemia

Figure 8: Sources Used for Diagnosed Incident Cases of Hospitalized Hypoglycemia

Figure 9: Sources Used for Diagnosed Incident Cases of Non-Diabetic Hypoglycemia

Figure 10: Sources Used for Diagnosed Incident Cases of Bariatric Surgeries

Figure 11: Sources Used for Diagnosed Incident Cases of Hypoglycemia Among the Bariatric Surgery Population

Figure 12: Diagnosed Incident Cases of Hypoglycemia Attributed to T1D, 7MM, Men and Women, All Ages, 2020

Figure 13: 7MM, Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T1D, Men and Women, 2020 (N)

Figure 14: 7MM, Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T1D, All Ages, 2020 (N)

Figure 15: 7MM, Diagnosed Incident Cases of Hypoglycemia Attributed to T1D by Severity, Men and Women, All Ages, 2020 (N)

Figure 16: 7MM, Hospitalized Severe Incident Cases of Hypoglycemia Attributed to TID, Men and Women, All Ages, 2020 (N)

Figure 17: Diagnosed Incident Cases of Hypoglycemia Attributed to T2D, 7MM, Men and Women, All Ages, 2020

Figure 18: 7MM, Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T2D, Men and Women, 2020 (N)

Figure 19: 7MM, Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T2D, All Ages, 2020 (N)

Figure 20: 7MM, Diagnosed Incident Cases of Hypoglycemia Attributed to T2D by Severity, Men and Women, All Ages, 2020 (N)

Figure 21: 7MM, Hospitalized Severe Incident Cases of Hypoglycemia Attributed to T2D, Men and Women, All Ages, 2020 (N)

Figure 22: Diagnosed Incident Cases of Hypoglycemia Attributed to T1D and T2D, 7MM, Men and Women, All Ages, 2020

Figure 23: 7MM, Age-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T1D and T2D, Men and Women, 2020 (N)

Figure 24: 7MM, Sex-Specific Diagnosed Incident Cases of Hypoglycemia Attributed to T1D and T2D, All Ages, 2020 (N)

Figure 25: 7MM, Diagnosed Incident Cases of Hypoglycemia Attributed to T1D and T2D by Severity, Men and Women, All Ages, 2020 (N)

Figure 26: 7MM, Hospitalized Severe Incident Cases of Hypoglycemia Attributed to T1D and T2D, Men and Women, All Ages, 2020 (N)

Figure 27: 7MM, Diagnosed Incident Cases of Non-Diabetic Hypoglycemia, Men and Women, All Ages, 2020 (N)

Figure 28: Diagnosed Incident Cases of Hypoglycemia in the Bariatric Surgery Population, 7MM, Men and Women, All Ages, 2020

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