Contract Manufacturing Service Agreements – Rising Manufacturing Opportunities Driven by Pharmaceutical Pipeline Expansion

This report is a brand new publication covering contract service agreements, across a range of different services and manufacturing scales. The number of contract service agreements secured serves as a primary indicator of a CMO's performance. Contract Manufacturing Service Agreements is critical for establishing an understanding of the overall CMO industry, the range of services provided and the features of some of the largest CMOs participating in the industry.

Scope

This 51-page report gives an important expert quantitative analysis on the contract manufacturing industry. Findings are based on the industry’s most comprehensive databases of the CMO industry (GlobalData’s Databases of Contract Service Providers and Deals) this analysis is primarily driven by the Deals Database, which is continuously updated and reveals manufacturing relationships for Pharma products and the types of services offered. The 14 figures and 5 tables throughout the report illustrate major points and trends.

This report is required reading for:

• CMO executives who must have deep understanding of the novel approvals landscape to make strategic planning and investment decisions.

• Sourcing and procurement executives who must understand crucial components of the supply base in order to make decisions about supplier selection and management.

• Private equity investors that need a deeper understanding of the market to identify and value potential investment targets.

Reasons to buy

Overview of CSAs and the levels of outsourcing associated with different services and drug type

Detailed view of CDMO performance by CSAs and an assessment of their CSAs manufacturing scale from GlobalData’s Deals database

Manufacturing Agreements for different molecule types, RoA and by sponsor company market cap have all been assessed.

Analysis of regulatory designations such as those with Orphan, Breakthrough or Fast Track designations and assessment of outsourcing

Companies mentioned

89bio

3P Biopharmaceuticals

A+ Secure Packaging

Abcuro

Abdi Ibrahim Ilac Sanayi ve Ticaret

ABL Bio

Ablynx

Abzena

AC Immune

Academic Pharmaceuticals

Acadia Pharmaceuticals

AcelRx Pharmaceuticals

ACS Dobfar

Acumen Pharmaceuticals

Acura Pharmaceuticals

AdAlta

Adial Pharmaceuticals

Adoh

Adrenas Therapeutics

ADT Pharmaceuticals

Advent Bioservices

Advicenne

Aenova Holding

Affibody

AGC Biologics

Agilent Technologies

Aimmune Therapeutics

Ajinomoto

Akari Therapeutics

Akcea Therapeutics

Akebia Therapeutics

Akero Therapeutics

Albany Molecular Research

Albemarle

Alcami

Alchem Laboratories

Aldevron

Alector

AlfaSigma

Alkermes

Allpack Group

Almac Group

Alnylam Pharmaceuticals

Alvotech

AMAG Pharmaceuticals

Amatsigroup SAS

Amgen

Amicus Therapeutics

Ammtek

Amneal Pharmaceuticals

Amplia Therapeutics

Applied Therapeutics

Aprea Therapeutics

Aprinoia Therapeutics

Aptahem

Aptuit

Aptuit LLC

Aravive Biologics

Arbor Pharmaceuticals

Arch Biopartners

Ardena Holding

Argenx

Argonaut Manufacturing Services

Aridis Pharmaceuticals

ArTara Therapeutics

Artelo Biosciences

ASC Therapeutics

Ascletis

Aslan Pharmaceuticals

ASM – Aerosol-Service

AstraZeneca

Asymchem Laboratories

Athenex

Atossa Therapeutics

Aucta Pharmaceuticals

Aurinia Pharmaceuticals

Autolus Therapeutics

Avacta Group

AveXis

Avid Bioservices

Avion Pharmaceuticals

Axim Biotechnologies

Axovant Gene Therapies

Ayl

Aytu BioScience

AzarGen Biotechnologies

Bachem Holding

Bausch & Lomb Pharmaceuticals

Baxter International

BeiGene (Beijing)

BerGenBio

Bioasis Technologies

Biogen

Bioglan

Biohaven Pharmaceutical Holding Company

BioIent International

BioMarin Pharmaceutical

BioPharmX

Biophore India Pharmaceuticals

Biotechpharma

BJ Bioscience

Blue Water Vaccines

Blueprint Medicines

Boehringer Ingelheim Biopharmaceuticals

BriaCell Therapeutics

Bridge Therapeutics

BridgeBio Pharma

BSP Pharmaceuticals

Caladrius Biosciences

Cambrex

Camurus

Cancer Research UK; Hummingbird Bioscience Pte

Candel Therapeutics

Cantargia

Carton Service

Catalent

Catalyst Biosciences

Cell Therapies

Cell Therapy Catapult

Cellectis

CELLforCURE

Celltrion

Center Pharmaceutical Specialties

Chiasma

Chiesi Farmaceutici

Chongqing Pharmaceutical Research Institute

Cinfa Biotech

Citryll

CKD Bio

Clinical Supplies Management

Clovis Oncology

CMAB Biopharma

CNS Pharmaceuticals

Coalition for Epidemic Preparedness Innovations; Public Health Vaccines

Cobra Biologics

Cognate BioServices

Coherus BioSciences

CombiGene

Comprehensive Cell Solutions

Consort Medical

Contract Pharmaceutical Services of Australia

Contract Pharmaceuticals

CoreRx

CPC Scientific

CSBio

Cytodyn

Cytovance Biologics

Cyxone

Daiichi Sankyo

Dalton Pharma Services

Delmar Chemicals

Dermavant Sciences

Destiny Pharma

Dexcel PT Israel

DiaMedica Therapeutics

DiNAQOR

Divi's Laboratories

Dizal (Jiangsu) Pharmaceutical

Dongkook Pharmaceutical

Doppel Farmaceutici

Dova Pharmaceuticals

Dow Development Laboratories

DPT Laboratories

DURECT

Eczacibasi Monrol Nukleer Urunler Tic ve San

Eisai

EMD Serono

Emergent BioSolutions

Endo International Plc

Endocyte

Enochian Biosciences

Enzyvant Sciences

Epizyme

Esperion Therapeutics

Esteve Pharmaceuticals

Eutilex

Evonik Industries

Excella

ExCellThera

F. Hoffmann-La Roche

Fabbrica Italiana Sintetici

Fareva

Farmabios

Ferndale Pharma Group

Ferring International Center

Fidson Healthcare

Foamix Pharmaceuticals

Follicum

Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung

Freeline Therapeutics

Fresenius

Frontier Biotechnologies

Fujifilm Diosynth Biotechnologies USA

Gamida Cell

GB Sciences

Genemedicine

Genentech

Geneos Therapeutics

GeneQuantum Healthcare (Suzhou)

Genethon

Genmab

Genprex

Genscript Biotech

German Red Cross Blood Donor Service

GI Innovation

Gilead Sciences

Glatt

GlaxoSmithKline

Glycotope

Goodwin Biotechnology

GP Pharm

Grunenthal

GW Pharmaceuticals

Hansa Biopharma

Harbour BioMed

Harpoon Therapeutics

Hillstream BioPharma

Hitachi Chemical

Hookipa Pharma

Horizon Therapeutics

Hoth Therapeutics

Hovione FarmaCiencia

Hubei Haosun Pharmaceutical

Hummingbird Bioscience

iBio

Ichnos Sciences

Icon Bioscience

IDT Biologika

IGM Biosciences

I-Mab Biopharma

Immune Pharmaceuticals

ImmuneOncia Therapeutics

Immunos Therapeutics

IMPACT Therapeutics

Importfab

Indapta Therapeutics

Indivior

Inmune Bio

Insmed

Intec Pharma

Intercept Pharmaceuticals

International Isotopes

Ionic Pharmaceuticals

Iovance Biotherapeutics

iProgen Biotech

IriSys

Iroko Pharmaceuticals

Ironshore Pharmaceuticals and Development

IsoTherapeutics Group

ITG Isotope Technologies Garching

IVERIC bio

JanOne

Janssen Pharmaceuticals

Jazz Pharmaceuticals

JDP Therapeutics

Jenner Institute

Jerome Stevens Pharmaceuticals

Jubilant HollisterStier Contract Manufacturing

Just Evotec Biologics

Kamada

Kangstem Biotech

KannaLife Sciences

Karuna Therapeutics

Karyopharm Therapeutics

KBI Biopharma

King's College London

Kiniksa Pharmaceuticals

Kitov Pharma

Kyowa Kirin

L.E.A.F. Pharmaceuticals

La Jolla Pharmaceutical Company

Laboratoire Elaiapharm

Laurus Labs

Lava Therapeutics

Les Laboratoires Servier

LGC

LGM Pharma

Life Science Outsourcing

Liquidia Technologies

List Biological Laboratories

LobSor Pharmaceuticals

Lonza Group

Loxo Oncology

LTS Lohmann Therapie-Systeme

Lubrizol Life Science Health

Lyophilization Services of New England

MacroGenics

MassBiologics

MaSTherCell

Matrisys Bioscience

MaxCyte

MedPharm

Melinta Therapeutics

Merck

Meridian Medical Technologies

Mesoblast

Metacel Pharmaceuticals

MGB Biopharma

MIAS Pharma

Mikart

MilliporeSigma

Minerva Neurosciences

Mission Bio

Moleculin Biotech

Molteni Farmaceutici

Monopar Therapeutics

Mycenax Biotech

Mylan

Myovant Sciences

Nabriva Therapeutics

Nabriva Therapeutics

NBE-Therapeutics

NervGen Pharma

NGM Biopharmaceuticals

Niels Clauson- Kaas

NLS Pharmaceutics

Noramco

Nordmark Arzneimittel

Novan

Novartis

Novartis International

Novasep Holding

Novast Holdings

Novavax

Novetide

Novex Innovations

NovImmune

NuGenerex Immuno-Oncology

Oakrum Pharma

Oasmia Pharmaceutical

OishiKoseidorp

Oligomerix

Ology Bioservices

Omeros

OncoImmune

OncoResponse

Opiant Pharmaceuticals

OptiNose US

Orexigen Therapeutics

Orion

Orphelia Pharma

Otsuka Holdings

Outlook Therapeutics

Oxford BioMedica

Palatin Technologies

Patheon

Pathovax LLC

PCI Pharma Services

PEPTONIC medical

Perrigo

Pfizer

Pharmaceutics International

Pharmasol

PharmaZell

PhaseBio Pharmaceuticals

Phathom Pharmaceuticals

Phoenix Molecular Designs

Piramal Pharma Solutions

PolyPeptide Group

Portola Pharmaceuticals

Poseida Therapeutics

Prestige BioPharma

Prevail Therapeutics

Probiogen

Procos

Profectus BioSciences

Progenics Pharmaceuticals

Propak Health

Protherics UK

Provention Bio

PTC Therapeutics

Puma Biotechnology

Purdue Pharma

Q BioMed

Qpharma

QPS Holdings

Quotient Sciences

RadImmune Therapeutics

Rechon Life Science

Rechon Life Science

Recipharm

Recipharm

Recipharm (Aesica Pharmaceuticals)

RedHill Biopharma

RegenxBio

Regis Technologies

Renaissance Pharma

Rentschler Biopharma

Rentschler Fill Solutions

RespireRx Pharmaceuticals

Rexgenero

Rhythm Pharmaceuticals

Richter-Helm BioLogics

Rigel Pharmaceuticals

Rocket Pharmaceuticals

ROMEG Therapeutics

Rottendorf Pharma

Sagent Pharmaceuticals

Salix Pharmaceuticals

Samsung Bioepis

Samsung Biologics

SanBio Company

Sandoz

Sanofi

Sanquin Blood Supply Foundation

Santen Pharmaceutical

Sarepta Therapeutics

Sartorius Stedim Cellca

Satsuma Pharmaceuticals

Saudi Pharmaceutical Industries & Medical Appliances

Scilex Pharmaceuticals

ScinoPharm Taiwan

Seibersdorf Labor

Selexis

Sequential Medicine

Servier Laboratories

Sesen Bio

Shanghai ChemPartner

Shanghai Zhongxi Pharmaceutical

Sharp Packaging Services

Sheba Medical Center

Shenzhen Fapon Biopharma

Shinlin Sinseng Pharmaceutical

Shionogi

Shire

SHL Group

Siegfried Hameln

SIGA Technologies

Sonnet BioTherapeutics

Spark Therapeutics

SpectronRx

SpringWorks Therapeutics

St Renatus

Stcube

Stemline Therapeutics

Sterling Pharma Solutions

Stoke Therapeutics

Sun Pharmaceutical Industries

SutroVax

Suzhou Kintor Pharmaceuticals

Syngene International

Synthorx

TaiMed Biologics

Taimed Biologics USA

Taiwan Liposome

Takara Bio

Takeda Pharmaceutical

TCR2 Therapeutics

Tedor Pharma

Telix Pharmaceuticals

Tetraphase Pharmaceuticals

Teva Pharmaceutical Industries

TFF Pharmaceuticals

The National Institute of Allergy and Infectious Diseases

The Ritedose Corp

Therapeutics

TherapeuticsMD

Theravance Biopharma

Theravectys

Thermo Fisher Scientific (Patheon Viral Vector Services)

Titan Pharmaceuticals

Tocagen

Toyobo

Trefoil Therapeutics

Trevena

Tricida

Triphase Accelerator

UCB

Ultragenyx Pharmaceutical

UNC Lineberger Comprehensive Cancer Center

Unither Pharmaceuticals

Univar Solutions

Uquifa

UroGen Pharmaceuticals

US WorldMeds

Vaccinex

Valerius Biopharma

Valneva Sweden

Vaxart

Verastem

Vertex Pharmaceuticals

Vetter Pharma-Fertigung

VGXI

Viela Bio

ViGene Biosciences

Vir Biotechnology

Viscofan BioEngineering

Vivus

Wacker Chemie

Wavelength Enterprises

Windtree Therapeutics

WuXi AppTec

Xenikos

Xenon Pharmaceuticals

XERIS Pharmaceuticals

Xynomic Pharmaceuticals Holdings

Y-mAbs Therapeutics

Yposkesi

Yung Shin Pharmaceuticals Ind

Zambon

Zenopharm

Zhittya Genesis Medicine

Zogenix

Zosano Pharma

Zumutor Biologics

Table of Contents

1 Table of Contents

2 List of Tables

3 List of Figures

4 Executive Summary

5 Introduction

6 Contract Service Agreements Overview

7 Contract Services Offered and Manufacturing Scale

7.1 API Manufacturing Contract Service Agreements

7.2 Dose Manufacturing Contract Service Agreements

8 Contract Service Agreements by Therapy Area

9 Special Product Categories

10 Outsourcing by Sponsor Market Cap

11 CMO Performance

12 What It Means

12.1 Insights on Services Offered, Scale of Production, and CSA Relationships

12.2 Top CMO Players

12.3 Sponsor Market Cap Relationships to Outsourcing

12.4 Varying Levels of Public Disclosure

13 Notes on Methodology

14 Appendix

14.1 Appendix Tables

14.2 Bibliography

14.3 Primary Research – Key Opinion Leaders in this Report

14.4 About the Authors

14.5 Contact Us

14.6 Disclaimer

List of Tables

Table 1: Contract Service Agreements Offering More than One Manufacturing Service, 2018–2020

Table 2: Scale of Therapy Area Contract Service Agreements, 2018–2020

Table 3: Sponsor Type by Services Offered in Contract Service Agreements, 2018–2020

Table 4: Most Active Sponsors by Contract Service Agreements, 2018–2020

Table 5: Contract Service Agreements, 2018–2020

List of Figures

Figure 1: Scale of Contract Service Agreements, 2018–2020

Figure 2: Contract Service Agreements by Year, January 2018 – March 2020

Figure 3: Quantity of Services Offered Per Contract Service Agreement, 2018–2020

Figure 4: Quantity of Drugs Outsourced Per Contract Service Agreement, 2018–2020

Figure 5: Specific Services Outsourced in the Contract Service Agreements 2018–2020

Figure 6: Contract Service Agreements for Clinical-Scale API Manufacturing, 2018–2020

Figure 7: Contract Service Agreements for Commercial-Scale API Manufacturing, 2018–2020

Figure 8: Outsourced Dose Manufacturing by Molecule Type, 2018–2020

Figure 9: CSAs for Dose Manufacturing by Route of Administration, 2018–2020

Figure 10: Contract Service Agreements by Therapy Area, 2018–2020

Figure 11: Contract Service Agreements by Special Designation, 2018–2020

Figure 12: Contract Service Agreements by Sponsor Market Cap, 2018–2020

Figure 13: Most Active CMOs by Contract Service Agreements by Year, 2018–2020

Figure 14: Most Active CMOs by Contract Service Agreements by Scale, 2018–2020

    Pricing

Discounts available for multiple report purchases.

reportstore@globaldata.com
+44 20 7947 2745

Join our mailing list

Saved reports