Interventional Neurology – Medical Devices Pipeline Assessment, 2017

Interventional Neurology includes devices for the treatment of intracranial aneurysms. This category includes devices used during the treatment of aneurysms which are aneurysm clips, embolization and coiling devices, navigational systems and neurovascular stents. GlobalData's Medical Devices sector report, “Interventional Neurology – Medical Devices Pipeline Assessment, 2017" provides comprehensive information about the Interventional Neurology pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress.

Scope

The Interventional Neurology Pipeline Assessment report provides key information and data related to:

• Extensive coverage of the Interventional Neurology under development.

• Review details of major pipeline products which include product description, licensing and collaboration details and other developmental activities including pipeline territories, regulatory paths and estimated approval dates.

• Reviews of major players involved in the pipeline product development.

• Provides key clinical trial data related to ongoing clinical trials such as trial phase, trial status, trial start and end dates, and, the number of trials of the major Interventional Neurology pipeline products.

• Review of Recent Developments in the segment / industry.

Reasons to buy

The Interventional Neurology Pipeline Assessment report enables you to:

• Access significant competitor information, analysis, and insights to improve your R&D strategies.

• Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.

• Identify and understand important and diverse types of Interventional Neurology under development.

• Formulate market-entry and market expansion strategies.

• Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline.

Companies mentioned

Alcyone Lifesciences Inc

Amnis Therapeutics Ltd

Anaconda BioMed SL

Aneuclose LLC

Apeliotus Technologies

Arterain Medical Inc (Inactive)

Avantec Vascular Corporation

BioCure, Inc.

Ceretrieve Ltd

Codman & Shurtleff Inc

Collagen Matrix Inc

Cordis Corp

CranioVation

CVTec Cerebrovascular Technologies GmbH

Dartmouth College

DePuy Synthes Inc

EchoGuide Medical, Inc. (Inactive)

Ecole Polytechnique Federale de Lausanne

Gaudi Vascular, Inc.

Hansen Medical Inc

Hansjorg Wyss Institute for Biologically Inspired Engineering

Hibernia Medical

Insera Therapeutics, LLC

InspireMD Inc

Medikit Co Ltd

Medtronic plc

Merlin MD Pte. Ltd.

Metactive Medical LLC

MicroPort Scientific Corp

MicroVention, Inc.

MindFrame Inc

MiVi Neuroscience, LLC

MRI Interventions Inc

NEOS Surgery SL

Neuravi Ltd

NeuroInterventional Therapeutics, Inc.

NeuroInterventions

Neurosigma Inc

Neurosyntec LLC. (Inactive)

NexGen Medical Systems Inc

NSVascular, Inc.

Oxford Endovascular Limited

Palmaz Scientific Inc

Penumbra Inc

Philips Healthcare

PhotoThera Inc (Inactive)

Pulsar Vascular, Inc.

Pulse Therapeutics Inc

Rapid Medical

Rontis AG

Shape Memory Therapeutics, Inc.

Sree Chitra Tirunal Institute for Medical Sciences & Technology

Strategic Polymer Sciences, Inc

Taewoong Medical Co Ltd

Terumo Corp

Triticum Medical Ltd.

Twin Star Medical Inc

University of California Los Angeles

University of California San Francisco

University of Minnesota

University of South Florida

University of Wisconsin Madison

University of Wolverhampton

Valor Medical Inc

Vascular Solutions Inc

Viket Medical Corporation

Weill Cornell Medical College

Zoll Medical Corporation

Table of Contents

1 Table of Contents 2

1.1 List of Tables 9

1.2 List of Figures 14

2 Introduction 16

2.1 Interventional Neurology Overview 16

3 Products under Development 17

3.1 Interventional Neurology – Pipeline Products by Stage of Development 17

3.2 Interventional Neurology – Pipeline Products by Segment 18

3.3 Interventional Neurology – Pipeline Products by Territory 19

3.4 Interventional Neurology – Pipeline Products by Regulatory Path 20

3.5 Interventional Neurology – Pipeline Products by Estimated Approval Date 21

3.6 Interventional Neurology – Ongoing Clinical Trials 22

4 Interventional Neurology – Pipeline Products under Development by Companies 23

4.1 Interventional Neurology Companies – Pipeline Products by Stage of Development 23

4.2 Interventional Neurology – Pipeline Products by Stage of Development 26

5 Interventional Neurology Companies and Product Overview 29

5.1 Alcyone Lifesciences Inc Company Overview 29

5.1.1 Alcyone Lifesciences Inc Pipeline Products & Ongoing Clinical Trials Overview 29

5.2 Amnis Therapeutics Ltd Company Overview 30

5.2.1 Amnis Therapeutics Ltd Pipeline Products & Ongoing Clinical Trials Overview 30

5.3 Anaconda BioMed SL Company Overview 33

5.3.1 Anaconda BioMed SL Pipeline Products & Ongoing Clinical Trials Overview 33

5.4 Aneuclose LLC Company Overview 34

5.4.1 Aneuclose LLC Pipeline Products & Ongoing Clinical Trials Overview 34

5.5 Apeliotus Technologies Company Overview 36

5.5.1 Apeliotus Technologies Pipeline Products & Ongoing Clinical Trials Overview 36

5.6 Arterain Medical Inc (Inactive) Company Overview 37

5.6.1 Arterain Medical Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 37

5.7 Avantec Vascular Corporation Company Overview 38

5.7.1 Avantec Vascular Corporation Pipeline Products & Ongoing Clinical Trials Overview 38

5.8 BioCure, Inc. Company Overview 40

5.8.1 BioCure, Inc. Pipeline Products & Ongoing Clinical Trials Overview 40

5.9 Ceretrieve Ltd Company Overview 41

5.9.1 Ceretrieve Ltd Pipeline Products & Ongoing Clinical Trials Overview 41

5.10 Codman & Shurtleff Inc Company Overview 42

5.10.1 Codman & Shurtleff Inc Pipeline Products & Ongoing Clinical Trials Overview 42

5.11 Collagen Matrix Inc Company Overview 45

5.11.1 Collagen Matrix Inc Pipeline Products & Ongoing Clinical Trials Overview 45

5.12 Cordis Corp Company Overview 46

5.12.1 Cordis Corp Pipeline Products & Ongoing Clinical Trials Overview 46

5.13 CranioVation Company Overview 47

5.13.1 CranioVation Pipeline Products & Ongoing Clinical Trials Overview 47

5.14 CVTec Cerebrovascular Technologies GmbH Company Overview 48

5.14.1 CVTec Cerebrovascular Technologies GmbH Pipeline Products & Ongoing Clinical Trials Overview 48

5.15 Dartmouth College Company Overview 49

5.15.1 Dartmouth College Pipeline Products & Ongoing Clinical Trials Overview 49

5.16 DePuy Synthes Inc Company Overview 51

5.16.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 51

5.17 EchoGuide Medical, Inc. (Inactive) Company Overview 53

5.17.1 EchoGuide Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 53

5.18 Ecole Polytechnique Federale de Lausanne Company Overview 54

5.18.1 Ecole Polytechnique Federale de Lausanne Pipeline Products & Ongoing Clinical Trials Overview 54

5.19 Gaudi Vascular, Inc. Company Overview 55

5.19.1 Gaudi Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 55

5.20 Hansen Medical Inc Company Overview 56

5.20.1 Hansen Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 56

5.21 Hansjorg Wyss Institute for Biologically Inspired Engineering Company Overview 57

5.21.1 Hansjorg Wyss Institute for Biologically Inspired Engineering Pipeline Products & Ongoing Clinical Trials Overview 57

5.22 Hibernia Medical Company Overview 58

5.22.1 Hibernia Medical Pipeline Products & Ongoing Clinical Trials Overview 58

5.23 Insera Therapeutics, LLC Company Overview 59

5.23.1 Insera Therapeutics, LLC Pipeline Products & Ongoing Clinical Trials Overview 59

5.24 InspireMD Inc Company Overview 60

5.24.1 InspireMD Inc Pipeline Products & Ongoing Clinical Trials Overview 60

5.25 Medikit Co Ltd Company Overview 61

5.25.1 Medikit Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 61

5.26 Medtronic plc Company Overview 65

5.26.1 Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 65

5.27 Merlin MD Pte. Ltd. Company Overview 72

5.27.1 Merlin MD Pte. Ltd. Pipeline Products & Ongoing Clinical Trials Overview 72

5.28 Metactive Medical LLC Company Overview 73

5.28.1 Metactive Medical LLC Pipeline Products & Ongoing Clinical Trials Overview 73

5.29 MicroPort Scientific Corp Company Overview 74

5.29.1 MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 74

5.30 MicroVention, Inc. Company Overview 80

5.30.1 MicroVention, Inc. Pipeline Products & Ongoing Clinical Trials Overview 80

5.31 MindFrame Inc Company Overview 89

5.31.1 MindFrame Inc Pipeline Products & Ongoing Clinical Trials Overview 89

5.32 MiVi Neuroscience, LLC Company Overview 90

5.32.1 MiVi Neuroscience, LLC Pipeline Products & Ongoing Clinical Trials Overview 90

5.33 MRI Interventions Inc Company Overview 91

5.33.1 MRI Interventions Inc Pipeline Products & Ongoing Clinical Trials Overview 91

5.34 NEOS Surgery SL Company Overview 92

5.34.1 NEOS Surgery SL Pipeline Products & Ongoing Clinical Trials Overview 92

5.35 Neuravi Ltd Company Overview 94

5.35.1 Neuravi Ltd Pipeline Products & Ongoing Clinical Trials Overview 94

5.36 NeuroInterventional Therapeutics, Inc. Company Overview 98

5.36.1 NeuroInterventional Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 98

5.37 NeuroInterventions Company Overview 99

5.37.1 NeuroInterventions Pipeline Products & Ongoing Clinical Trials Overview 99

5.38 Neurosigma Inc Company Overview 100

5.38.1 Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 100

5.39 Neurosyntec LLC. (Inactive) Company Overview 101

5.39.1 Neurosyntec LLC. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 101

5.40 NexGen Medical Systems Inc Company Overview 102

5.40.1 NexGen Medical Systems Inc Pipeline Products & Ongoing Clinical Trials Overview 102

5.41 NSVascular, Inc. Company Overview 103

5.41.1 NSVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 103

5.42 Oxford Endovascular Limited Company Overview 104

5.42.1 Oxford Endovascular Limited Pipeline Products & Ongoing Clinical Trials Overview 104

5.43 Palmaz Scientific Inc Company Overview 105

5.43.1 Palmaz Scientific Inc Pipeline Products & Ongoing Clinical Trials Overview 105

5.44 Penumbra Inc Company Overview 106

5.44.1 Penumbra Inc Pipeline Products & Ongoing Clinical Trials Overview 106

5.45 Philips Healthcare Company Overview 109

5.45.1 Philips Healthcare Pipeline Products & Ongoing Clinical Trials Overview 109

5.46 PhotoThera Inc (Inactive) Company Overview 110

5.46.1 PhotoThera Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 110

5.47 Pulsar Vascular, Inc. Company Overview 115

5.47.1 Pulsar Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 115

5.48 Pulse Therapeutics Inc Company Overview 116

5.48.1 Pulse Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 116

5.49 Rapid Medical Company Overview 119

5.49.1 Rapid Medical Pipeline Products & Ongoing Clinical Trials Overview 119

5.50 Rontis AG Company Overview 120

5.50.1 Rontis AG Pipeline Products & Ongoing Clinical Trials Overview 120

5.51 Shape Memory Therapeutics, Inc. Company Overview 121

5.51.1 Shape Memory Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 121

5.52 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 123

5.52.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 123

5.53 Strategic Polymer Sciences, Inc Company Overview 124

5.53.1 Strategic Polymer Sciences, Inc Pipeline Products & Ongoing Clinical Trials Overview 124

5.54 Taewoong Medical Co Ltd Company Overview 125

5.54.1 Taewoong Medical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 125

5.55 Terumo Corp Company Overview 126

5.55.1 Terumo Corp Pipeline Products & Ongoing Clinical Trials Overview 126

5.56 Triticum Medical Ltd. Company Overview 128

5.56.1 Triticum Medical Ltd. Pipeline Products & Ongoing Clinical Trials Overview 128

5.57 Twin Star Medical Inc Company Overview 129

5.57.1 Twin Star Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 129

5.58 University of California Los Angeles Company Overview 130

5.58.1 University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 130

5.59 University of California San Francisco Company Overview 133

5.59.1 University of California San Francisco Pipeline Products & Ongoing Clinical Trials Overview 133

5.60 University of Minnesota Company Overview 134

5.60.1 University of Minnesota Pipeline Products & Ongoing Clinical Trials Overview 134

5.61 University of South Florida Company Overview 135

5.61.1 University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 135

5.62 University of Wisconsin Madison Company Overview 136

5.62.1 University of Wisconsin Madison Pipeline Products & Ongoing Clinical Trials Overview 136

5.63 University of Wolverhampton Company Overview 138

5.63.1 University of Wolverhampton Pipeline Products & Ongoing Clinical Trials Overview 138

5.64 Valor Medical Inc Company Overview 139

5.64.1 Valor Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 139

5.65 Vascular Solutions Inc Company Overview 140

5.65.1 Vascular Solutions Inc Pipeline Products & Ongoing Clinical Trials Overview 140

5.66 Viket Medical Corporation Company Overview 141

5.66.1 Viket Medical Corporation Pipeline Products & Ongoing Clinical Trials Overview 141

5.67 Weill Cornell Medical College Company Overview 142

5.67.1 Weill Cornell Medical College Pipeline Products & Ongoing Clinical Trials Overview 142

5.68 Zoll Medical Corporation Company Overview 143

5.68.1 Zoll Medical Corporation Pipeline Products & Ongoing Clinical Trials Overview 143

6 Interventional Neurology- Recent Developments 144

6.1 May 11, 2017: Healthcare Veteran John Fletcher Joins MRI Interventions’ Board of Directors 144

6.2 May 09, 2017: Penumbra Reports First Quarter 2017 Financial Results 144

6.3 May 09, 2017: Voyager Therapeutics Reports First Quarter 2017 Financial Results and Corporate Highlights 145

6.4 May 04, 2017: AxoGen Reports 2017 First Quarter Financial Results 146

6.5 Apr 27, 2017: Boston Scientific Announces Results For First Quarter 2017 147

6.6 Apr 27, 2017: MRI Interventions Announces 2017 First Quarter Results 148

6.7 Apr 27, 2017: Merit Medical Reports Results for First Quarter of 2017 150

6.8 Apr 25, 2017: Stryker reports first quarter 2017 results 151

6.9 Apr 24, 2017: Publication Provides Guidelines to Reduce Transportation Risks Associated with Neurosurgical Laser Ablation Multi-site Workflows 152

6.10 Apr 24, 2017: Medtronic Announces Most Advanced StealthStation for Neurosurgery 153

6.11 Apr 24, 2017: Anaconda Biomed Engages Creganna Medical 154

6.12 Apr 24, 2017: Nexstim Appoints Hanna Kotola as VP of Legal Affairs 154

6.13 Apr 23, 2017: Bard Announces First Quarter Results 154

6.14 Apr 21, 2017: Penumbra Appoints Bridget O'Rourke to its Board of Directors 155

6.15 Apr 19, 2017: ClearPoint Neuro Navigation System’s Real-time MRI Guided Platform to be Featured at AANS Practical Clinics for Fourth Consecutive Year 156

6.16 Apr 19, 2017: Johnson & Johnson reports Q1 2017 results 156

6.17 Apr 18, 2017: Johnson & Johnson Reports 2017 First-Quarter Results 158

6.18 Apr 11, 2017: Stroke patients in England set to receive revolutionary new treatment 160

6.19 Apr 06, 2017: MRI Interventions Announces Record Quarterly Revenue, Record ClearPoint System Procedures in 2017 First Quarter 161

6.20 Apr 06, 2017: MRI Interventions Announces Record Quarterly Revenue, Record ClearPoint System Procedures in 2017 First Quarter 162

6.21 Apr 04, 2017: $3.6 million to fund personalized 3-D brain maps to guide neurosurgeries 162

6.22 Mar 30, 2017: MPSC Announces 2016 Annual Results 164

6.23 Mar 28, 2017: Nexstim: The decisions of the Board of Directors 165

6.24 Mar 23, 2017: Synaptive Medical Expands Medtech Expertise Through Board Additions 166

6.25 Mar 21, 2017: Metactive Medical Announces Issuance of Patent on Ballstent Embolization Device 167

6.26 Mar 20, 2017: MicroPort NeuroTech Hosts WILLIS Academic Symposium 167

6.27 Mar 15, 2017: Voyager Therapeutics Reports Fourth Quarter and Full Year 2016 Financial Results and Corporate Highlights 168

6.28 Mar 13, 2017: Cook Medical Announces Umesh Patel as President of Cook Biotech 171

6.29 Mar 09, 2017: Changes in Nexstim Management Team 171

6.30 Mar 07, 2017: MicroVention And Terumo Announce Data From Multicenter GREAT Study 171

6.31 Mar 07, 2017: Anteo Technologies Announces Verification Study With Cook Medical Australia 172

6.32 Feb 28, 2017: Nexstim: Financial Statement Release 2016 173

6.33 Feb 28, 2017: MRI Interventions Announces 2016 Fourth Quarter and Full Year Results 175

6.34 Feb 28, 2017: Penumbra Reports Fourth Quarter and Full Year 2016 Financial Results 178

6.35 Feb 28, 2017: Government of Canada Invests in Research to Advance Patient Care 179

6.36 Feb 23, 2017: New Solitaire Stent Retriever Study Validates Outcomes and Real-World Application of Stroke Treatment Best Practices 180

6.37 Feb 22, 2017: Independent Study Supports Use of Penumbra Aspiration as Frontline Thrombectomy Therapy for Acute Ischemic Stroke 181

6.38 Feb 22, 2017: AxoGen Reports 2016 Fourth Quarter and Full Year Financial Results 182

6.39 Feb 21, 2017: Neuravi Announces Completion of Patient Enrollment in Clinical Trial of a Novel Stent Retriever for Acute Ischemic Stroke 184

6.40 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 185

6.41 Feb 21, 2017: Merit Medical Reports Results for Fourth Quarter and Year Ended December 31, 2016 188

6.42 Feb 16, 2017: InspireMD Provides Year End Business Update and Reports Financial Results for the Fourth Quarter and Year Ended December 31, 2016 189

6.43 Feb 14, 2017: MicroPort Receives CFDA Approval for APOLLO Intracranial Stent System in Large Sizes 190

6.44 Feb 09, 2017: Terumo Announces Change of Executive Officers 190

6.45 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 191

6.46 Feb 02, 2017: Boston Scientific Announces Results For Fourth Quarter And Full Year Ended December 31, 2016 192

6.47 Jan 31, 2017: Terumo Opens a Branch in Yangon 194

6.48 Jan 26, 2017: Bard Announces Fourth Quarter Results 194

6.49 Jan 24, 2017: Stryker reports 2016 results and 2017 outlook 195

6.50 Jan 24, 2017: Johnson & Johnson Reports 2016 Fourth-Quarter Results 196

6.51 Jan 24, 2017: MRI Interventions Announces Year-End Update, Including 2016 Fourth Quarter and Full Year Revenues 199

6.52 Jan 16, 2017: MicroPort Attends 19th Annual Meeting of China Health Economics Association 200

6.53 Jan 10, 2017: Stryker provides 2016 preliminary net sales results 200

6.54 Jan 09, 2017: Anaconda BioMed Appoints Mr. Giovanni Leo to its Advisory Board 202

6.55 Jan 09, 2017: AxoGen Preannounces Estimated Fourth Quarter and Full Year 2016 Revenue 202

6.56 Jan 09, 2017: Johnson & Johnson Medical Devices Companies Launch CareAdvantage, a Suite of Holistic, Insights-Driven Capabilities to Help U.S. Health Systems Navigate Value-Based Care 203

6.57 Jan 05, 2017: AxoGen Appoints Ivica Ducic Medical Director 204

6.58 Jan 05, 2017: Voyager Therapeutics Elects Wendy Dixon, Ph.D. and Glenn Pierce, M.D., Ph.D. to Board of Directors 204

6.59 Jan 04, 2017: MRI Interventions’ ClearPoint Surpasses Single-Year Milestone of 500 Procedures in 2016 205

6.60 Jan 03, 2017: Amnis Therapeutics Starts its First Clinical Trial with its Neuro Thrombectomy Device 206

6.61 Jan 03, 2017: Voyager Therapeutics Appoints Jane Pritchett Henderson as Chief Financial Officer 206

6.62 Dec 22, 2016: Nexstim pre-close business update 207

6.63 Dec 19, 2016: MRI Interventions’ ClearPoint Neuro Navigation System to be Utilized in Medicenna Therapeutics’ Phase 2 MDNA55 Clinical Trial for the Treatment of Recurrent Glioblastoma 208

6.64 Dec 19, 2016: Penumbra Appoints Thomas C. Wilder to its Board of Directors 208

6.65 Dec 15, 2016: MicroPort NeuroTech Attends CINS 2016 209

6.66 Dec 12, 2016: Silk Road Medical Announces Updated Clinical Data on TCAR Presented at the 44th Annual VEITH Symposium 210

6.67 Dec 12, 2016: Terumo Formulates 5-Year Mid- to Long-term Growth Strategy 211

6.68 Dec 08, 2016: MRI Interventions’ ClearPoint Neuro Navigation System Utilized in Voyager Therapeutics’ VY-AADC01 Phase 1b Trial; Positive Interim Results Reported 211

6.69 Dec 05, 2016: MRI Interventions’ ClearPoint Neuro Navigation System to be Exhibited at Pediatric Neurosurgical Conference 212

6.70 Nov 28, 2016: MRI Interventions’ ClearPoint Neuro Navigation System to be Featured at the American Epilepsy Society Meeting 212

6.71 Nov 24, 2016: MicroPort NeuroTech Attends 2016 CCVF 213

6.72 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 213

6.73 Nov 22, 2016: Collagen Matrix Names Oystein Valberg as Chief Financial Officer 216

6.74 Nov 16, 2016: Medtronic's Solitaire Stent Retriever Device Receives Expanded Indication from the U.S. Food and Drug Administration for the Reduction of Stroke-Related Disability 217

6.75 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 218

6.76 Nov 15, 2016: Penumbra Announces Resignation of Board Member 218

6.77 Nov 15, 2016: BTG: Interim results 218

6.78 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 219

6.79 Nov 14, 2016: InspireMD Reports Financial Results for the Third Quarter Ended September 30, 2016 220

6.80 Nov 10, 2016: Voyager Therapeutics Provides Third Quarter 2016 Investor Update 222

6.81 Nov 04, 2016: MRI Interventions Announces 2016 Third Quarter and Nine Month Results 224

6.82 Nov 03, 2016: Penumbra Reports Third Quarter 2016 Financial Results 227

6.83 Nov 02, 2016: AxoGen Reports Financial Results for Third Quarter 2016 228

6.84 Oct 27, 2016: Stryker reports third quarter 2016 results 229

6.85 Oct 26, 2016: Boston Scientific Announces Results For Third Quarter 2016 230

6.86 Oct 26, 2016: Synaptive Medical to Showcase BrightMatter Technology at North American Spine Society in Boston 232

6.87 Oct 26, 2016: Merit Medical Reports Sales Up

15.3% for the Quarter Ended September 30, 2016 232

6.88 Oct 25, 2016: Bard Announces Third Quarter Results 233

6.89 Oct 24, 2016: Vascular Solutions Reports Third Quarter Results 234

6.90 Oct 21, 2016: MRI Interventions and Texas Biomedical Research Institute Demonstrate Precise Delivery and Increased Viability of Neural Stem Cell Transplantation Utilizing the ClearPoint Neuro-Navigation System 236

6.91 Oct 18, 2016: Johnson & Johnson Reports 2016 Third-Quarter Results 237

6.92 Oct 17, 2016: University of Pittsburgh Medical Center (UPMC) Completes its 75th MRI Guided Procedure With MRI Interventions’ ClearPoint Neuro-Navigation System 239

6.93 Oct 14, 2016: Medtronic Announces Voluntary Recall of Its Pipeline Embolization Device, Alligator Retrieval Device, X-Celerator Hydrophilic Guidewire, Ultraflow and Marathon Flow Directed Micro Catheters 239

6.94 Oct 10, 2016: Professor Ian Meredith To Join Boston Scientific As Executive Vice President And Global Chief Medical Officer 240

6.95 Oct 06, 2016: BTG: close period update 241

6.96 Sep 27, 2016: Amnis has completed the product testing process for its novel retrieval device 241

6.97 Sep 21, 2016: MRI Interventions’ ClearPoint Neuro-Navigation System to be Featured at the Congress of Neurological Surgeons (“CNS”), in a Hands-On Workshop Entitled, “Laser Ablation Surgery Practical Clinic” 242

6.98 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 242

6.99 Sep 15, 2016: Silk Road Medical Announces New Medicare Coverage Option for TransCarotid Artery Revascularization Procedures 243

6.100 Sep 12, 2016: AxoGen to Participate at the American Association of Oral and Maxillofacial Surgeons 98th Annual Meeting 244

6.101 Sep 08, 2016: Rapid Medical's Comaneci Adjustable Remodeling Mesh Exceeds 500 Successful Aneurysm Treatments 245

6.102 Sep 07, 2016: Neuravi Announces European Launch of EmboTrap II Stent Retriever for the Treatment of Acute Stroke 246

6.103 Sep 07, 2016: InspireMD Appoints Thomas Kester to Board of Directors 246

6.104 Sep 02, 2016: FDA allows marketing of clot retrieval devices to reduce disability in stroke patients 247

6.105 Aug 31, 2016: Cook Medical Names Jean-Marc Creissel Vice President of Operations in Greater China 248

6.106 Aug 30, 2016: MPSC Announces 2016 Interim Results 248

6.107 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 250

6.108 Aug 15, 2016: MRI Interventions Announces 2016 Second Quarter and Six Month Results 252

6.109 Aug 09, 2016: Penumbra Reports Second Quarter 2016 Financial Results 256

6.110 Aug 09, 2016: InspireMD Reports Financial Results for the Second Quarter Ended June 30, 2016 257

6.111 Aug 03, 2016: AxoGen Reports Financial Results for Second Quarter 2016 259

6.112 Jul 28, 2016: Boston Scientific Announces Results For Second Quarter 2016 260

6.113 Jul 27, 2016: Randomized Penumbra 3D Trial of Next Generation Stent Retriever Meets Primary Endpoints 262

6.114 Jul 27, 2016: BTG Announces Appointment of Non-executive Director 263

6.115 Jul 27, 2016: Merit Medical Reports Sales Up

9.4% for the Quarter Ended June 30, 2016 263

6.116 Jul 26, 2016: Merit Medical Announces Appointment of New Director 264

6.117 Jul 26, 2016: Bard Announces Second Quarter Results 264

6.118 Jul 25, 2016: Vascular Solutions Reports Second Quarter Results 265

6.119 Jul 25, 2016: Neuravi Selects Robert Colloton to Lead U.S. Commercialization of Innovative Stent Retriever 268

6.120 Jul 21, 2016: Stryker reports second quarter 2016 results 269

6.121 Jul 21, 2016: InspireMD Regains Compliance With NYSE MKT Listing Standards 270

6.122 Jul 19, 2016: Penumbra Announces Key Events at Society of NeuroInterventional Surgery 2016 Meeting 271

6.123 Jul 19, 2016: Johnson & Johnson Reports 2016 Second-Quarter Results 271

6.124 Jul 14, 2016: BTG: Annual General Meeting 273

6.125 Jul 13, 2016: WILLIS Granted Market Approval in Thailand 274

6.126 Jul 13, 2016: Boston Scientific Elects Yoshiaki Fujimori to Board of Directors 274

6.127 Jul 05, 2016: Synaptive Medical Receives Health Canada Approval for BrightMatter Guide: a Surgical Navigation Solution 275

6.128 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 276

6.129 Jun 24, 2016: Collagen Matrix Names Bill Messer as Vice President, Sales and Marketing 277

6.130 Jun 23, 2016: MRI Interventions ClearPoint Neuro Navigation Technology Highlighted in Voyager Therapeutics Interim Parkinson’s Disease Gene Therapy Study Results 277

6.131 Jun 22, 2016: Johnson & Johnson Announces Retirement of Louise Mehrotra and Appointment of Joseph Wolk as Vice President of Investor Relations 278

6.132 Jun 15, 2016: Silk Road Medical Announces Updated Clinical Data on TCAR Presented at the 2016 Society for Vascular Surgery Annual Meeting 279

6.133 Jun 15, 2016: MRI Interventions’ ClearPoint Neuro Navigation System to be Featured at ASSFN Biennial Meeting 280

6.134 Jun 08, 2016: Boston Scientific Announces Restructuring Program to Support Long-Term Growth and Innovation 281

6.135 Jun 07, 2016: MRI Interventions’ ClearPoint Neuro Navigation System Utilized for the First Time at Childrens Healthcare of Atlanta 281

6.136 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 282

6.137 Jun 03, 2016: LEPUCARE established in India 283

6.138 May 31, 2016: MRI Interventions’ ClearPoint Neuro Navigation System Utilized for the First Time at Inova Fairfax Hospital 283

6.139 May 31, 2016: Amnis Therapeutics announces receiving a grant of

1.5 million NIS for the “Golden Retriever” from the Israeli Chief Scientist 283

6.140 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 284

7 Appendix 288

7.1 Methodology 288

7.2 About GlobalData 291

7.3 Contact Us 291

7.4 Disclaimer 291

List of Tables

Table 1: Interventional Neurology – Pipeline Products by Stage of Development 16

Table 2: Interventional Neurology – Pipeline Products by Segment 17

Table 3: Interventional Neurology – Pipeline Products by Territory 18

Table 4: Interventional Neurology – Pipeline Products by Regulatory Path 19

Table 5: Interventional Neurology – Pipeline Products by Estimated Approval Date 20

Table 6: Interventional Neurology – Ongoing Clinical Trials 21

Table 7: Interventional Neurology Companies – Pipeline Products by Stage of Development 22

Table 8: Interventional Neurology – Pipeline Products by Stage of Development 25

Table 9: Alcyone Lifesciences Inc Pipeline Products & Ongoing Clinical Trials Overview 28

Table 12: Amnis Therapeutics Ltd Pipeline Products & Ongoing Clinical Trials Overview 29

Table 17: Anaconda BioMed SL Pipeline Products & Ongoing Clinical Trials Overview 32

Table 20: Aneuclose LLC Pipeline Products & Ongoing Clinical Trials Overview 33

Table 25: Apeliotus Technologies Pipeline Products & Ongoing Clinical Trials Overview 35

Table 28: Arterain Medical Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 36

Table 31: Avantec Vascular Corporation Pipeline Products & Ongoing Clinical Trials Overview 37

Table 36: BioCure, Inc. Pipeline Products & Ongoing Clinical Trials Overview 39

Table 39: Ceretrieve Ltd Pipeline Products & Ongoing Clinical Trials Overview 40

Table 42: Codman & Shurtleff Inc Pipeline Products & Ongoing Clinical Trials Overview 41

Table 51: Collagen Matrix Inc Pipeline Products & Ongoing Clinical Trials Overview 44

Table 54: Cordis Corp Pipeline Products & Ongoing Clinical Trials Overview 45

Table 57: CranioVation Pipeline Products & Ongoing Clinical Trials Overview 46

Table 60: CVTec Cerebrovascular Technologies GmbH Pipeline Products & Ongoing Clinical Trials Overview 47

Table 63: Dartmouth College Pipeline Products & Ongoing Clinical Trials Overview 48

Table 68: DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 50

Table 73: EchoGuide Medical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 52

Table 76: Ecole Polytechnique Federale de Lausanne Pipeline Products & Ongoing Clinical Trials Overview 53

Table 79: Gaudi Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 54

Table 82: Hansen Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 55

Table 85: Hansjorg Wyss Institute for Biologically Inspired Engineering Pipeline Products & Ongoing Clinical Trials Overview 56

Table 88: Hibernia Medical Pipeline Products & Ongoing Clinical Trials Overview 57

Table 91: Insera Therapeutics, LLC Pipeline Products & Ongoing Clinical Trials Overview 58

Table 94: InspireMD Inc Pipeline Products & Ongoing Clinical Trials Overview 59

Table 97: Medikit Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 60

Table 106: Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 64

Table 121: Merlin MD Pte. Ltd. Pipeline Products & Ongoing Clinical Trials Overview 71

Table 124: Metactive Medical LLC Pipeline Products & Ongoing Clinical Trials Overview 72

Table 127: MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 73

Table 140: MicroVention, Inc. Pipeline Products & Ongoing Clinical Trials Overview 79

Table 160: MindFrame Inc Pipeline Products & Ongoing Clinical Trials Overview 88

Table 163: MiVi Neuroscience, LLC Pipeline Products & Ongoing Clinical Trials Overview 89

Table 166: MRI Interventions Inc Pipeline Products & Ongoing Clinical Trials Overview 90

Table 169: NEOS Surgery SL Pipeline Products & Ongoing Clinical Trials Overview 91

Table 174: Neuravi Ltd Pipeline Products & Ongoing Clinical Trials Overview 93

Table 182: NeuroInterventional Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 97

Table 185: NeuroInterventions Pipeline Products & Ongoing Clinical Trials Overview 98

Table 188: Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 99

Table 191: Neurosyntec LLC. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 100

Table 194: NexGen Medical Systems Inc Pipeline Products & Ongoing Clinical Trials Overview 101

Table 197: NSVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 102

Table 200: Oxford Endovascular Limited Pipeline Products & Ongoing Clinical Trials Overview 103

Table 203: Palmaz Scientific Inc Pipeline Products & Ongoing Clinical Trials Overview 104

Table 206: Penumbra Inc Pipeline Products & Ongoing Clinical Trials Overview 105

Table 211: Philips Healthcare Pipeline Products & Ongoing Clinical Trials Overview 108

Table 214: PhotoThera Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 109

Table 227: Pulsar Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 114

Table 230: Pulse Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 115

Table 235: Rapid Medical Pipeline Products & Ongoing Clinical Trials Overview 118

Table 238: Rontis AG Pipeline Products & Ongoing Clinical Trials Overview 119

Table 241: Shape Memory Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 120

Table 246: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 122

Table 249: Strategic Polymer Sciences, Inc Pipeline Products & Ongoing Clinical Trials Overview 123

Table 252: Taewoong Medical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 124

Table 255: Terumo Corp Pipeline Products & Ongoing Clinical Trials Overview 125

Table 260: Triticum Medical Ltd. Pipeline Products & Ongoing Clinical Trials Overview 127

Table 263: Twin Star Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 128

Table 266: University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 129

Table 275: University of California San Francisco Pipeline Products & Ongoing Clinical Trials Overview 132

Table 278: University of Minnesota Pipeline Products & Ongoing Clinical Trials Overview 133

Table 281: University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 134

Table 284: University of Wisconsin Madison Pipeline Products & Ongoing Clinical Trials Overview 135

Table 289: University of Wolverhampton Pipeline Products & Ongoing Clinical Trials Overview 137

Table 292: Valor Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 138

Table 295: Vascular Solutions Inc Pipeline Products & Ongoing Clinical Trials Overview 139

Table 298: Viket Medical Corporation Pipeline Products & Ongoing Clinical Trials Overview 140

Table 301: Weill Cornell Medical College Pipeline Products & Ongoing Clinical Trials Overview 141

Table 304: Zoll Medical Corporation Pipeline Products & Ongoing Clinical Trials Overview 142

Table 307: Glossary 28

List of Figures

Figure 1: Interventional Neurology – Pipeline Products by Stage of Development 17

Figure 2: Interventional Neurology – Pipeline Products by Segment 18

Figure 3: Interventional Neurology – Pipeline Products by Territory 19

Figure 4: Interventional Neurology – Pipeline Products by Regulatory Path 20

Figure 5: Interventional Neurology – Pipeline Products by Estimated Approval Date 21

Figure 6: Interventional Neurology – Ongoing Clinical Trials 22

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