EpiCast Report: Sepsis and Septic Shock- Epidemiology Forecast to 2026

Sepsis is a life-threatening complication arising from an infection, which occurs when the body’s response to the infection damages its own tissues and organs. Sepsis can lead to multiple organ failure and death, especially if it is not recognized early and treated promptly. Anyone can develop sepsis; however, the condition is more common among children less than one year of age, older adults, and those with weakened immune systems. Although any type of infection (bacterial, viral, or fungal) can lead to sepsis, people suffering from pneumonia, abdominal infection, kidney infection, and bloodstream infection (bacteremia) are more likely to develop sepsis. The most common pathogens for sepsis include bacteria (gram-positive, gram-negative), fungi, viruses, and parasites.

To forecast the diagnosed incident cases of sepsis and septic shock in the 7MM, GlobalData epidemiologists selected nationally representative population-based studies that provided diagnosed incidence and/or mortality rate of sepsis and septic shock in the 7MM. Additionally, the diagnostic criteria for sepsis and septic shock are based on the sepsis-3 definition across all 7MM in this analysis.

GlobalData epidemiologists forecast that the diagnosed incident cases of sepsis in the 7MM will grow at an Annual Growth Rate (AGR) of 2.06% per year over the next 10 years, from 2,594,665 cases in 2016 to 3,129,753 cases in 2026. GlobalData epidemiologists forecast that the diagnosed incident cases of septic shock in the 7MM will grow by an AGR of 2.07% per year over the next 10 years, from 539,085 cases in 2016 to 650,426 cases in 2026. The US will have the highest incident cases of sepsis and septic shock in the 7MM throughout the forecast period, while Japan had the lowest.

Scope

The Sepsis and Septic Shock EpiCast Report and EpiCast Model provide an overview of the risk factors and global trends of sepsis and septic shock in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiological forecast for the diagnosed incident cases of sepsis and septic shock, segmented by age (for all ages) and sex. The sepsis and septic shock diagnosed incident cases are further segmented by causative agent and organ dysfunction. Additionally, GlobalData epidemiologists provide a forecast for the in-hospital mortality cases of sepsis and septic shock, segmented by age for both sexes.

The sepsis and septic shock epidemiology report and model were written and developed by Masters- and PhD-level epidemiologists.

The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.

The EpiCast Model is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.

Reasons to buy

The Sepsis and Septic Shock EpiCast series will allow you to:

Develop business strategies by understanding the trends shaping and driving the global sepsis and septic shock market.

Quantify patient populations in the global sepsis and septic shock market to improve product design, pricing, and launch plans.

Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for sepsis and septic shock therapeutics in each of the markets covered.

Understand the causative agent, organ dysfunction, and mortality of sepsis and septic shock

Table of Contents

Table of Contents

1 Table of Contents

1.1 List of Tables

1.2 List of Figures

2 Executive Summary

2.1 Related Reports

2.2 Upcoming Reports

3 Epidemiology

3.1 Disease Background

3.2 Risk Factors and Comorbidities

3.3 Global and Historical Trends

3.4 Forecast Methodology

3.4.1 Sources

3.4.2 Forecast Assumptions and Methods

3.4.3 Diagnosed Incident Cases of Sepsis

3.4.4 Diagnosed Incident Cases of Septic Shock

3.4.5 Diagnosed Incident Cases of Sepsis/Septic Shock by Causative Agent

3.4.6 Organ Dysfunction among Diagnosed Incident Cases of Sepsis

3.4.7 Organ Dysfunction among Diagnosed Incident Cases of Septic Shock

3.4.8 Sepsis In-Hospital Mortality Cases

3.4.9 Septic Shock In-Hospital Mortality Cases

3.5 Epidemiological Forecast for Sepsis and Septic Shock (2016–2026)

3.5.1 Diagnosed Incident Cases of Sepsis

3.5.2 Age-Specific Diagnosed Incident Cases of Sepsis

3.5.3 Sex-Specific Diagnosed Incident Cases of Sepsis

3.5.4 Diagnosed Incident Cases of Sepsis by Causative Agent

3.5.5 Organ Dysfunction among Diagnosed Incident Cases of Sepsis

3.5.6 Sepsis In-Hospital Mortality Cases

3.5.7 Age-Specific In-Hospital Mortality Cases of Sepsis

3.5.8 Diagnosed Incident Cases of Septic Shock

3.5.9 Age-Specific Diagnosed Incident Cases of Septic Shock

3.5.10 Sex-Specific Diagnosed Incident Cases of Septic Shock

3.5.11 Diagnosed Incident Cases of Septic Shock by Causative Agent

3.5.12 Organ Dysfunction among Diagnosed Incident Cases of Septic Shock

3.5.13 Septic Shock In-Hospital Mortality Cases

3.5.14 Age-Specific In-Hospital Mortality Cases of Septic Shock

3.6 Discussion

3.6.1 Epidemiological Forecast Insight

3.6.2 Limitations of Analysis

3.6.3 Strengths of Analysis

4 Appendix

4.1 Bibliography

4.2 About the Authors

4.2.1 Epidemiologist

4.2.2 Reviewers

4.2.3 Global Director of Therapy Analysis and Epidemiology

4.2.4 Global Head and EVP of Healthcare Operations and Strategy

4.3 About GlobalData

4.4 Contact Us

4.5 Disclaimer

List of Tables

Table 1: Risk Factors and Comorbidities for Sepsis and Septic Shock

Table 2: 7MM, Diagnosed Incident Cases of Sepsis, Both Sexes, All Ages, Selected Years 2016–2026

Table 3: 7MM, Sepsis In-Hospital Mortality Cases, Both Sexes, All Ages, Selected Years 2016–2026

Table 4: 7MM, Diagnosed Incident Cases of Septic Shock, Both Sexes, All Ages, Selected Years 2016–2026

Table 5: 7MM, Septic Shock In-Hospital Mortality Cases, Both Sexes, All Ages, Selected Years 2016–2026

List of Figures

Figure 1: 7MM, Diagnosed Incident Cases of Sepsis, Both Sexes, All Ages, 2016 and 2026

Figure 2: 7MM, Diagnosed Incident Cases of Septic Shock, Both Sexes, All Ages, 2016 and 2026

Figure 3: 7MM, Age-Standardized Diagnosed Incidence of Sepsis (Cases per 100,000 Population), Both Sexes, All Ages, 2016

Figure 4: 7MM, Age-Standardized Diagnosed Incidence of Septic Shock (Cases per 100,000 Population), Both Sexes, All Ages, 2016

Figure 5: 7MM, Sources Used and Not Used, Diagnosed Incident Cases of Sepsis

Figure 6: 7MM, Sources Used and Not Used, Diagnosed Incident Cases of Sepsis/Septic Shock by Causative Agent

Figure 7: 7MM, Sources Used and Not Used, Organ Dysfunction among Sepsis Cases

Figure 8: 7MM, Sources Used and Not Used, In-Hospital Mortality Cases of Sepsis

Figure 9: 7MM, Sources Used and Not Used, Diagnosed Incident Cases of Septic Shock

Figure 10: 7MM, Sources Used and Not Used, Organ Dysfunction of Septic Shock Cases

Figure 11: 7MM, Sources Used, In-Hospital Mortality Cases of Septic Shock

Figure 12: 7MM, Age-Specific Diagnosed Incident Cases of Sepsis, Both Sexes, All Ages, 2016

Figure 13: 7MM, Sex-Specific Diagnosed Incident Cases of Sepsis, Both Sexes, All Ages, 2016

Figure 14: 7MM, Diagnosed Incident Cases of Sepsis by Causative Agent, Both Sexes, All Ages, 2016

Figure 15: 7MM, Organ Dysfunction among Diagnosed Incident Cases of Sepsis, Both Sexes, All Ages, 2016

Figure 16: 7MM, Age-Specific In-Hospital Mortality Cases of Sepsis, Both Sexes, All Ages, 2016

Figure 17: 7MM, Age-Specific Diagnosed Incident Cases of Septic Shock, Both Sexes, All Ages, 2016

Figure 18: 7MM, Sex-Specific Diagnosed Incident Cases of Septic Shock, Both Sexes, All Ages, 2016

Figure 19: 7MM, Diagnosed Incident Cases of Septic Shock by Causative Agent, Both Sexes, All Ages, 2016

Figure 20: 7MM, Organ Dysfunction among Diagnosed Incident Cases of Septic Shock, Both Sexes, All Ages, 2016

Figure 21: 7MM, Age-Specific In-Hospital Mortality Cases of Septic Shock, Both Sexes, All Ages, 2016

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