EpiCast Report: Dermatophytic Onychomycosis – Epidemiology Forecast to 2022

Dermatophytic onychomycosis (DO) is an infection of the nail fold or nail plate with dermatophytes, a type of fungus, especially Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton flocossom (Sterry et al., 2006). DO begins as a white/yellow spot under the tip of the nail. As the infection spreads deeper, it causes further discoloration and thickening of the nail, resulting in nail disfigurement and pain/discomfort.

The high worldwide prevalence of DO is primarily due to changes in factors relating to lifestyle, customs, and culture. The incidence and prevalence of DO in the EU was stable over a period of 30 years between the 1960s and 1990s due to a decline in industries such as coal mining, representing decreased use of industrial baths, while simultaneously there has been an increase in prevalence resulting from the use of communal recreational facilities, which led to a constant incidence of DO (Roberts, 1992; Seebacher et al., 2008). In Japan, the traditional Japanese practice of walking barefoot in the house, which facilitates the spread of the infection to family members, is the primary reason for the especially high prevalence and intensity of toenail fungal disease in Japan (Nishimoto, 2006; Watanabe et al., 2010).

Scope

The Dermatophytic Onychomycosis (DO) EpiCast Report provides an overview of the risk factors and global trends of DO in the seven major markets (US, France, Germany, Italy, Spain, UK, and Japan). It also includes a 10-year epidemiology forecast of the prevalent cases of DO, segmented by sex, and age (15–29 years, 30–49 years, 50–69 years, and >70 years) in these markets.

Reasons to buy

Develop business strategies by understanding the trends shaping and driving the global DO market.

Quantify patient populations in the global DO market to improve product design, pricing, and launch plans.

Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for DO therapeutics in each of the markets covered.

Table of Contents

1Table of Contents1

1.1List of Tables2

1.2List of Figures2

2Executive Summary3

3Introduction5

3.1Catalyst5

3.2Upcoming Reports5

4Epidemiology6

4.1Risk Factors and Comorbidities6

4.1.1Poor peripheral circulation is greater in older men6

4.1.2Household contact with other DO patients increases risk of infection

2.5 times7

4.1.3Immunosuppression increases susceptibility to DO infections7

4.1.4Prevalence of dermatophytic onychomycosis is higher in diabetics than in non-diabetics7

4.2Global Trends8

4.2.1US8

4.2.25EU8

4.2.3Japan9

4.3Forecast Methodology10

4.3.1Sources Used11

4.3.2Forecast Assumptions and Methods12

4.3.3Sources Not Used13

4.4Epidemiology Forecast (2012–2022)14

4.4.1Prevalent Cases of Dermatophytic Onychomycosis14

4.4.2Age-Specific Prevalent Cases of Dermatophytic Onychomycosis16

4.4.3Sex-Specific Prevalent Cases of Dermatophytic Onychomycosis17

4.4.4Age-Standardized Prevalence of Dermatophytic Onychomycosis18

4.5Discussion19

4.5.1Limitations of the Analysis20

4.5.2Strengths of the Analysis20

5Appendix21

5.1Bibliography21

5.2About the Authors24

5.2.1Epidemiologists24

5.2.2Reviewers24

5.2.3Global Director of Epidemiology and Clinical Trials Analysis25

5.2.4Global Head of Healthcare25

5.3About GlobalData25

5.4About EpiCast25

5.5Contact Us26

5.6Disclaimer26

List of Tables

Table 1: Risk Factors and Comorbidities for Dermatophytic Onychomycosis6

Table 2: Seven Major Markets, Sources of Dermatophytic Onychomycosis Prevalence Data10

Table 3: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, Ages =15 Years, Men and Women, Selected Years, 2012–202214

Table 4: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, by Age, Men and Women, N = Millions (Row %), 201216

Table 5: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, by Sex, Ages = 15 Years, N=Millions, (Row %), 201217

List of Figures

Figure 1: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, Ages =15 Years, Males and Females, 2012 and 20223

Figure 2: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, Ages =15 Years, Men and Women, Selected Years, 2012–202215

Figure 3: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, by Age, Men and Women, N = Millions, 201217

Figure 4: Seven Major Markets, Total Prevalent Cases of Dermatophytic Onychomycosis, by Sex, Ages = 15 Years, N = Millions, 201218

Figure 5: Seven Major Markets, Age-Standardized Prevalence of Dermatophytic Onychomycosis, Ages =15 Years, by Sex , 201219

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