Pharmaceutical & Healthcare Annual Deals Analysis: M&A and Investments Trends – 2019

GlobalData's “Pharmaceutical & Healthcare Annual Deals Analysis: M&A and Investments Trends – 2019” report is an essential source of data and trend analysis on partnerships, licensing, mergers and acquisitions (M&As) and financings in the pharmaceuticals industry. The report provides detailed information on partnership and licensing transactions, M&As, equity/debt offerings, private equity, and venture financing registered in the pharmaceuticals industry in the year 2019. The report portrays detailed comparative data on the number of deals and their value in the last five years, subdivided by deal types, various therapy areas, and geographies. Additionally, the report provides information on the top financial advisory firms in the pharmaceuticals industry.

Data presented in this report is derived from GlobalData’s proprietary in-house Pharma Intelligence Center deals database and primary and secondary research.

Scope

Analysis of the market trends for the pharmaceutical industry in the global arena.

Review of deal trends in the cardiovascular, central nervous system, dermatology, ear nose throat disorders, gastrointestinal, genito urinary system and sex hormones, hematological disorders, hormonal disorders, immunology, infectious disease, male health, metabolic disorders, mouth and dental disorders, musculoskeletal, oncology, ophthalmology, respiratory, toxicology, and women's health segments.

Analysis of partnerships, licensing, M&As, equity/debt offerings, private equity, and venture financing deals in the pharmaceutical industry.

Analysis of therapy areas which are very active in terms of venture capital financing, partnerships, licensing agreements, equity/debt offerings, and M&As.

Analysis of deals based on different payment modes, including upfront and milestone payments, primarily in partnerships and licensing agreements in the pharmaceutical industry.

Analysis of partnership and licensing deals based on clinical stage of development of products.

Summary of the pharmaceutical deals globally in the six months.

Information on the top deals happened in the pharmaceutical industry.

Geographies covered include – North America, Europe, Asia Pacific, South & Central America, and the Middle East & Africa.

League tables of financial advisors in M&As and equity/debt offerings. This includes key advisors such as Morgan Stanley, Credit Suisse, and Goldman Sachs.

Reasons to buy

Enhance your decision making capability in a more rapid and time sensitive manner.

Find out the major deal performing segments for investments in your industry.

Evaluate the types of companies which are entering into partnership or licensing agreements; divesting and acquiring assets.

Identify companies that are aggressively looking to raise capital in the market

Evaluate niche therapy areas that are receiving majority of the upfront and milestone payments in the pharmaceutical industry.

Identify the key venture capitalists, who are financing the pharmaceutical and biotech companies.

Evaluate the clinical development stages where majority of the partnerships and licensing agreements are happening.

Do deals with an understanding of how competitors are financed, and the mergers and partnerships that have shaped the pharmaceutical industry.

Identify growth segments and opportunities in each region within the industry.

Look for key financial advisors where you are planning to raise capital from the market or for acquisitions within the industry.

Table of Contents

1. Table of Contents

1. Table of Contents 2

1.1. List of Tables 6

1.2. List of Figures 9

2. Deal Values In Pharmaceutical & Healthcare Industry Increased In 2019 11

2.1. Pharmaceutical & Healthcare, Deals Summary, 2019 11

3. Pharmaceutical & Healthcare, Global, Deals Summary 16

3.1. Pharmaceutical & Healthcare, Global, Deals Analysis, 2019 16

3.1.1. Pharmaceuticals & Healthcare, Global, Deals Analysis, 2019 by Quarter 18

3.2. Pharmaceuticals & Healthcare, Global, by Type, Number of Deals, 2019 20

3.3. Pharmaceuticals & Healthcare, Global, by Type, Deal Values, 2019 21

3.4. Pharmaceuticals & Healthcare, Global, Top Deals, 2019 22

3.5. Pharmaceuticals & Healthcare, Top Deals, Global, Summaries, 2019 22

3.5.1. Shire Bristol-Myers Squibb Acquires Celgene 22

3.5.2. AbbVie to Acquire Allergan 23

3.5.3. AbbVie Raises USD30 Billion in Private Placement of Notes 25

3.5.4. Danaher to Acquire Biopharma Business from General Electric for USD21.4 Billion 25

3.5.5. Bristol-Myers Squibb Raises USD19 Billion in Private Placement of Notes 25

3.5.6. Amgen Acquires Rights to Otezla from Celgene for USD13.4 Billion 26

3.5.7. Pfizer Acquires Array BioPharma 26

3.5.8. Consortium of Investors Acquire Nestle Skin Health from Nestle for USD10.11 Billion 27

3.5.9. Novartis Acquires Medicines Co 27

3.5.10. Eli Lilly Acquires Loxo Oncology for USD8 Billion 28

4. Pharmaceuticals & Healthcare, Global, Deal Summary, by Type 29

4.1. Pharmaceuticals & Healthcare, Global, M&A, 2019 29

4.1.1. Pharmaceuticals & Healthcare, Global, M&A, 2019 by Quarter 31

4.1.2. Top M&A Deals in 2019 32

4.1.3. Pharmaceuticals & Healthcare, Global, M&A Deals, by Therapy Area, 2019 33

4.2. Pharmaceuticals & Healthcare, Global, Equity Offering Deals, 2019 34

4.2.1. Pharmaceuticals & Healthcare, Global, Equity Offering Deals, 2019 by Quarter 36

4.2.2. Pharmaceuticals & Healthcare, Global, IPO Deals, 2019 37

4.2.3. Top IPOs in 2019 38

4.2.4. Pharmaceuticals & Healthcare, Global, Secondary Offerings Deals, 2019 39

4.2.5. Top Secondary Offerings in 2019 40

4.2.6. Pharmaceuticals & Healthcare, Global, PIPE Deals, 2019 41

4.2.7. Top PIPE Deals in 2019 42

4.2.8. Pharmaceuticals & Healthcare, Global, Equity Offering Deals, by Therapy Area, 2019 43

4.3. Pharmaceuticals & Healthcare, Global, Debt Offering Deals, 2019 44

4.3.1. Pharmaceuticals & Healthcare, Global Debt Offerings, 2019 by Quarter 46

4.3.2. Pharmaceuticals & Healthcare, Global, Public Debt Offerings, 2019 47

4.3.3. Top Public Debt Offerings in 2019 48

4.3.4. Pharmaceuticals & Healthcare, Global, Private Debt Placements, 2019 49

4.3.5. Top Private Debt Placements in 2019 50

4.3.6. Pharmaceuticals & Healthcare, Global, Debt Offering Deals, by Therapy Area, 2019 51

4.4. Pharmaceuticals & Healthcare, Global, Partnership Deals, 2019 52

4.4.1. Pharmaceuticals & Healthcare, Global, Partnership Deals, 2019 by Quarter 54

4.4.2. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, 2019 56

4.4.3. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Upfront & Milestone Payments and Deal Value (US$ m), 2019 57

4.4.4. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 58

4.4.5. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, Number Of Deals, 2019 59

4.4.6. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, Deal Values (US$ m), 2019 60

4.4.7. Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 61

4.4.8. Pharmaceuticals & Healthcare, Global, Top Partnership Deals, by Deal Values, 2019 63

4.4.9. Pharmaceuticals & Healthcare, Global, Top Partnership Deals, by Upfront Payment, 2019 63

4.4.10. Pharmaceuticals & Healthcare, Global, Top Partnership Deals, by Milestone Payment, 2019 64

4.5. Pharmaceuticals & Healthcare, Global, Licensing Agreements, 2019 65

4.5.1. Pharmaceuticals & Healthcare, Global, Licensing Agreements, 2019 by Quarter 66

4.5.2. Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, 2019 67

4.5.3. Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Upfront & Milestone Payments and Deal Value (US$ m), 2019 68

4.5.4. Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 69

4.5.5. Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, by Phase, Total Deal Values (US$ m), 2019 70

4.5.6. Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, by Phase, Total Deal Values (US$ m), 2019 71

4.5.7. Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Phase, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 72

4.5.8. Pharmaceuticals & Healthcare, Global, Top Licensing Agreements, by Deal Values, 2019 74

4.5.9. Pharmaceuticals & Healthcare, Global, Top Licensing Agreements, by Upfront Payment, 2019 74

4.5.10. Pharmaceuticals & Healthcare, Global, Top Licensing Agreements, by Milestone Payment, 2019 75

4.6. Pharmaceuticals & Healthcare, Global, Private Equity Deals, 2019 76

4.6.1. Pharmaceuticals & Healthcare, Global, Private Equity Deals, 2019 by Quarter 77

4.6.2. Top Private Equity Deals in 2019 78

4.6.3. Pharmaceuticals & Healthcare, Global, Private Equity Deals, by Therapy Area, 2019 79

4.7. Pharmaceuticals & Healthcare, Global, Venture Capital Deals, 2019 80

4.7.1. Pharmaceuticals & Healthcare, Global, Venture Financing Deals, 2019 by Quarter 81

4.7.2. Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Stage of Financing, 2019 82

4.7.3. Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Stage of Financing, 2019 83

4.7.4. Pharmaceuticals & Healthcare, Global, Venture Capital, by Therapy Area, 2019 84

4.7.5. Pharmaceuticals & Healthcare, Global, Top VC Backed Companies, Last One Year 85

4.7.6. Pharmaceuticals & Healthcare, Global, Top Venture Financing Firms, 2019 86

4.7.7. Top Venture Financing Deals in 2019 88

5. Pharmaceuticals & Healthcare, Global, Deal Summary, By Market 89

5.1. Pharmaceuticals & Healthcare, Global, Oncology Deals, 2019 89

5.1.1. Pharmaceuticals & Healthcare, Global, Oncology Deals, 2019 by Quarter 91

5.1.2. Oncology – Deals of the Year 92

5.2. Pharmaceuticals & Healthcare, Global, Central Nervous System Deals, 2019 94

5.2.1. Pharmaceuticals & Healthcare, Global, Central Nervous System Deals, 2019 by Quarter 96

5.2.2. Central Nervous System – Deals of the Year 97

5.3. Pharmaceuticals & Healthcare, Global, Infectious Disease Deals, 2019 100

5.3.1. Pharmaceuticals & Healthcare, Global, Infectious Disease Deals, 2019 by Quarter 102

5.3.2. Infectious Disease – Deals of the Year 103

5.4. Pharmaceuticals & Healthcare, Global, Immunology Deals, 2019 106

5.4.1. Pharmaceuticals & Healthcare, Global, Immunology Deals, 2019 by Quarter 108

5.4.2. Immunology – Deals of the Year 109

5.5. Pharmaceuticals & Healthcare, Global, Cardiovascular Deals, 2019 111

5.5.1. Pharmaceuticals & Healthcare, Global, Cardiovascular Deals, 2019 by Quarter 113

5.5.2. Cardiovascular – Deals of the Year 114

5.6. Pharmaceuticals & Healthcare, Global, Metabolic Disorders Deals, 2019 116

5.6.1. Pharmaceuticals & Healthcare, Global, Metabolic Disorders Deals, 2019 by Quarter 118

5.6.2. Metabolic Disorders – Deals of the Year 119

5.7. Pharmaceuticals & Healthcare, Global, Gastrointestinal Deals, 2019 121

5.7.1. Pharmaceuticals & Healthcare, Global, Gastrointestinal Deals, 2019 by Quarter 123

5.7.2. Gastrointestinal – Deals of the Year 124

6. Pharmaceuticals & Healthcare, Deal Summary, By Geography 126

6.1. Pharmaceuticals & Healthcare, North America Region, Deals, 2019 126

6.1.1. Pharmaceuticals & Healthcare, North America Region, Deals, 2019 by Quarter 128

6.1.2. North America – Deals of the Year 129

6.2. Pharmaceuticals & Healthcare, European Region Deals, 2019 132

6.2.1. Pharmaceuticals & Healthcare, Europe, Deals, 2019 by Quarter 134

6.2.2. Europe – Deals of the Year 135

6.3. Pharmaceuticals & Healthcare, Asia-Pacific Region, Deals, 2019 138

6.3.1. Pharmaceuticals & Healthcare, Asia-Pacific Region Deals, 2019 by Quarter 140

6.3.2. Asia-Pacific – Deals of the Year 141

6.4. Pharmaceuticals & Healthcare, Rest of the World (ROW) Deals, 2019 143

6.4.1. Pharmaceuticals & Healthcare, Rest of the World Deals, 2019 by Quarter 146

6.4.2. Rest of the World – Deals of the Year 148

7. Pharmaceuticals & Healthcare, Global, Top Financial Advisors 149

7.1. Pharmaceuticals & Healthcare, Global, Top Financial Advisors, M&A, 2019 149

7.2. Pharmaceuticals & Healthcare, Global, Top Financial Advisors, Equity Offerings, 2019 151

8. Further Information 153

8.1. Methodology 153

8.2. About GlobalData 153

8.3. Contact Us 154

8.4. Disclosure information 154

8.5. Disclaimer 154

List of Tables

1.1. List of Tables

Table 1: Pharmaceutical & Healthcare, Global, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 17

Table 2: Pharmaceuticals & Healthcare, Deals Summary, Global, Number of Deals and Deal Value (US$ m), Q1 2019-Q4 2019 19

Table 3: Pharmaceuticals & Healthcare, Global, Number Of Deals and Deal Values (%), 2019 21

Table 4: Pharmaceuticals & Healthcare, Top Deals, Global, 2019 22

Table 5: Pharmaceuticals & Healthcare, Global, M&A, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 30

Table 6: Pharmaceuticals & Healthcare, Global, M&A, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 31

Table 7: Pharmaceuticals & Healthcare, Global, Top M&A Deals, 2019 32

Table 8: Pharmaceuticals & Healthcare, Global, M&A, Deals Summary, Number of Deals and Deal Values (US$ m), by Therapy Area, 2019 33

Table 9: Pharmaceuticals & Healthcare, Global, Equity Offerings, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 35

Table 10: Pharmaceuticals & Healthcare, Global, Equity Offerings, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 36

Table 11: Pharmaceuticals & Healthcare, Global, IPO Deals, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 37

Table 12 Pharmaceuticals & Healthcare, Global, Top IPOs, 2019 38

Table 13: Pharmaceuticals & Healthcare, Global, Secondary Offerings, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 39

Table 14: Pharmaceuticals & Healthcare, Global, Top Secondary Offerings, 2019 40

Table 15: Pharmaceuticals & Healthcare, Global, PIPEs, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 41

Table 16: Pharmaceuticals & Healthcare, Global, Top PIPE Deals, 2019 42

Table 17: Pharmaceuticals & Healthcare, Global, Equity Offering Deals, Deals Summary, Number of Deals and Deal Values (US$ m), 2019 43

Table 18: Pharmaceuticals & Healthcare, Global, Debt Offering, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 45

Table 19: Pharmaceuticals & Healthcare, Global, Debt Offering, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 46

Table 20: Pharmaceuticals & Healthcare, Global, Public Debt Offerings, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 47

Table 21: Pharmaceuticals & Healthcare, Global, Top Public Debt Offerings, 2019 48

Table 22: Pharmaceuticals & Healthcare, Global, Private Debt Placements, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 49

Table 23: Pharmaceuticals & Healthcare, Global, Top Private Debt Placements, 2019 50

Table 24: Pharmaceuticals & Healthcare, Global, Debt Offering Deals, Summary, Number of Deals and Deal Values (US$ m), 2019 51

Table 25: Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), 2015 – 2019 53

Table 26: Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), Q1 2019–Q4 2019 54

Table 27: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 56

Table 28: Pharmaceuticals & Healthcare, Partnership Deals, Upfront & Milestone Payment and Deal Values (US$ m), 2019 57

Table 29: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, Upfront & Milestone Payment and Deal Values (US$ m), 2019 58

Table 30: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, 2019 60

Table 31: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Upfront & Milestone Payment and Deal Values (US$ m), 2019 62

Table 32: Pharmaceuticals & Healthcare, Global, Partnerships, Upfront & Milestone Payment and Deal Values (US$ m), 2019 63

Table 33: Pharmaceuticals & Healthcare, Global, Top Partnership Deals, by Upfront Payment, 2019 63

Table 34: Pharmaceuticals & Healthcare, Global, Top Partnership Deals, by Milestone Payment, 2019 64

Table 35: Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 65

Table 36: Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019–Q4 2019 66

Table 37: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 67

Table 38: Pharmaceuticals & Healthcare, Licensing Agreements, Upfront & Milestone Payments and Deal Values (US$ m), 2019 68

Table 39: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, Upfront & Milestone Payments and Deal Values (US$ m), 2019 69

Table 40: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, Q4 2015 – Q4 2019 71

Table 41: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 73

Table 42: Pharmaceuticals & Healthcare, Global, Partnerships, Upfront & Milestone Payment and Deal Values (US$ m), 2019 74

Table 43: Pharmaceuticals & Healthcare, Global, Top Licensing Agreements, by Upfront Payment, 2019 74

Table 44: Pharmaceutical & Healthcare, Global, Top Licensing Agreements, by Milestone Payment, 2019 75

Table 45: Pharmaceuticals & Healthcare, Global, Private Equity, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 76

Table 46: Pharmaceuticals & Healthcare, Global, Private Equity, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 77

Table 47: Pharmaceuticals & Healthcare, Global, Top Private Equity Deals, 2019 78

Table 48: Pharmaceuticals & Healthcare, Global, Private Equity Deals, by Therapy Area, Deals Summary, Number of Deals and Deal Values (US$ m), 2019 79

Table 49: Pharmaceuticals & Healthcare, Global, Venture Capital, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 80

Table 50: Pharmaceuticals & Healthcare, Global, Venture Capital, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 81

Table 51: Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Stage of Financing, Number Of Deals and Deal Values (%), 2019 83

Table 52: Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Therapy Area, Deals Summary, Number of Deals and Deal Values (US$ m), 2019 84

Table 53: Pharmaceutical & Healthcare, Global, Top VC Backed Companies, 2019 85

Table 54: Pharmaceuticals & Healthcare, Top Venture Financing Firms, Global, Number of Deals and Deal Value (US$ m), 2019 87

Table 55: Pharmaceuticals & Healthcare, Top Venture Financing Deals, Global, 2019 88

Table 56: Pharmaceuticals & Healthcare, Global, Oncology, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 90

Table 57: Pharmaceuticals & Healthcare, Global, Oncology, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 92

Table 58: Pharmaceuticals & Healthcare, Global, Central Nervous System, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 95

Table 59: Pharmaceuticals & Healthcare, Global, Central Nervous System, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 97

Table 60: Pharmaceuticals & Healthcare, Global, Infectious Disease, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 101

Table 61: Pharmaceuticals & Healthcare, Global, Infectious Disease, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 103

Table 62: Pharmaceuticals & Healthcare, Global, Immunology, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 107

Table 63: Pharmaceuticals & Healthcare, Global, Immunology, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 109

Table 64: Pharmaceuticals & Healthcare, Global, Cardiovascular, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 112

Table 65: Pharmaceuticals & Healthcare, Global, Cardiovascular, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 114

Table 66: Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 117

Table 67: Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 119

Table 68: Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 122

Table 69: Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 124

Table 70: Pharmaceuticals & Healthcare, North America, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 127

Table 71: Pharmaceuticals & Healthcare, North America, Deals Summary, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 129

Table 72: Pharmaceuticals & Healthcare, Europe, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 133

Table 73: Pharmaceuticals & Healthcare, European Region Deals, Deals Summary, Global, Number of Deals and Deal Value (US$ m), Q1 2019-Q4 2019 135

Table 74: Pharmaceuticals & Healthcare, Asia-Pacific, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 139

Table 75: Pharmaceuticals & Healthcare, Asia-Pacific Region Deals, Deals Summary, Global, Number of Deals and Deal Value (US$ m), Q1 2019-Q4 2019 141

Table 76: Pharmaceuticals & Healthcare, Rest of the World Deals, Deals Summary, Number of Deals and Deal Value (US$ m), 2015 – 2019 145

Table 77: Pharmaceuticals & Healthcare, Rest of the World Deals, Deals Summary, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 147

Table 78: Pharmaceuticals & Healthcare, Global,, Top Financial Advisors, M&A, Number of Deals and Deal Value (US$ m), 2019 150

Table 79: Pharmaceuticals & Healthcare, Global Top Financial Advisors, Equity Offerings, Number of Deals and Deal Value (US$ m), 2019 152

List of Figures

1.2. List of Figures

Figure 1: Pharmaceutical & Healthcare, Number of Deals, 2015–2019 12

Figure 2: Pharmaceutical & Healthcare, Number of Deals by Type, 2015-2019 13

Figure 3: Pharmaceutical & Healthcare, Number of Deals by Therapy Area, 2019 14

Figure 4: Pharmaceutical & Healthcare, Number of Deals by Region, 2019 15

Figure 5: Pharmaceutical & Healthcare, Global, Number of Deals and Deal Value (US$ m), 2015- 2019 16

Figure 6: Pharmaceuticals & Healthcare, Global, Number of Deals and Deal Value (US$ m), Q1 2019-Q4 2019 18

Figure 7: Pharmaceuticals & Healthcare, Global, Number Of Deals (%), 2019 20

Figure 8: Pharmaceuticals & Healthcare, Global, Deal Values (%), 2019 21

Figure 9 Pharmaceuticals & Healthcare, Global, M&A, Number of Deals and Deal Values (US$ m), 2015 – 2019 29

Figure 10 Pharmaceuticals & Healthcare, Global, M&A, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 31

Figure 11: Pharmaceuticals & Healthcare, Global, M&As, by Therapy Area, Number of Deals and Deal Values (US$ m), by Therapy Area, 2019 33

Figure 12: Pharmaceuticals & Healthcare, Global, Equity Offering Deals, Number of Deals and Deal Values (US$ m), 2015 – 2019 34

Figure 13: Pharmaceuticals & Healthcare, Global, Equity Offering Deals, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 36

Figure 14: Pharmaceuticals & Healthcare, Global, IPO Deals, Number of Deals and Deal Value (US$ m), 2015 – 2019 37

Figure 15: Pharmaceuticals & Healthcare, Global, Secondary Offerings Deals, Number of Deals and Deal Value (US$ m), 2015 – 2019 39

Figure 16: Pharmaceuticals & Healthcare, Global, PIPE Deals, Number of Deals and Deal Value (US$ m), 2015 – 2019 41

Figure 17: Pharmaceuticals & Healthcare, Global, Equity Offering Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 43

Figure 18: Pharmaceuticals & Healthcare, Global, Debt Offering Deals, Number of Deals and Deal Values (US$ m), 2015 – 2019 44

Figure 19: Pharmaceuticals & Healthcare, Global, Debt Offering Deals, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 46

Figure 20: Pharmaceuticals & Healthcare, Global, Public Debt Offering Deals, Number of Deals and Deal Value (US$ m), 2015 – 2019 47

Figure 21: Pharmaceuticals & Healthcare, Global, Private Debt Placements, Number of Deals and Deal Value (US$ m), 2015 – 2019 49

Figure 22: Pharmaceuticals & Healthcare, Global, Debt Offering Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 51

Figure 23: Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), 2015 – 2019 52

Figure 24: Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 54

Figure 25: Pharmaceuticals & Healthcare, Global, Partnership Deals Break down (%), 2019 55

Figure 26: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 56

Figure 27: Pharmaceuticals & Healthcare, Global, Partnership Deals, Upfront & Milestone Payments and Deal Values (US$ m), 2019 57

Figure 28: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Therapy Area, Upfront & Milestone Payment and Deal Values (US$ m), 2019 58

Figure 29: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, 2019 59

Figure 30: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, 2019 60

Figure 31: Pharmaceuticals & Healthcare, Global, Partnership Deals, by Phase, by Upfront & Milestone Payments and Deal Values (US$ m), 2019 61

Figure 32: Pharmaceuticals & Healthcare, Global, Licensing Agreements, Number of Deals and Deal Values (US$ m), 2015 – 2019 65

Figure 33: Pharmaceuticals & Healthcare, Global, Licensing Agreements, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 66

Figure 34: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, Number of Deals and Deal Values (US$ m), 2019 67

Figure 35: Pharmaceuticals & Healthcare, Global, Licensing Agreements, Upfront & Milestone Payments and Deal Values (US$ m), 2019 68

Figure 36: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Therapy Area, Upfront & Milestone Payment and Deal Values (US$ m), 2019 69

Figure 37: Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, by Phase, Number Of Deals, 2019 70

Figure 38: Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, by Phase, Deal Values (US$ m), 2019 71

Figure 39: Pharmaceuticals & Healthcare, Global, Licensing Agreements, by Phase, by Upfront & Milestone Payment and Deal Values (US$ m), 2019 72

Figure 40: Pharmaceuticals & Healthcare, Global, Private Equity, Number of Deals and Deal Values (US$ m), 2015 – 2019 76

Figure 41: Pharmaceuticals & Healthcare, Global, Private Equity, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 77

Figure 42: Pharmaceuticals & Healthcare, Global, Private Equity Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), by Therapy Area, 2019 79

Figure 43: Pharmaceuticals & Healthcare, Global, Venture Capital, Number of Deals and Deal Values (US$ m), 2015 – 2019 80

Figure 44: Pharmaceuticals & Healthcare, Global, Venture Capital, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 81

Figure 45: Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Stage of Financing, Number Of Deals (%), 2019 82

Figure 46: Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Stage of Financing, Deal Values (%), 2019 83

Figure 47: Pharmaceuticals & Healthcare, Global, Venture Capital Deals, by Therapy Area, Number of Deals and Deal Values (US$ m), by Therapy Area, 2019 84

Figure 48: Pharmaceuticals & Healthcare, Top Venture Financing Firms, Global, Number of Deals and Deal Value (US$ m), 2019 86

Figure 49: Pharmaceuticals & Healthcare, Global, Oncology, Number of Deals and Deal Values (US$ m), 2015 – 2019 89

Figure 50: Pharmaceuticals & Healthcare, Global, Oncology, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 91

Figure 51: Pharmaceuticals & Healthcare, Global, Central Nervous System, Number of Deals and Deal Values (US$ m), 2019, 2015 – 2019 94

Figure 52: Pharmaceuticals & Healthcare, Central Nervous System, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 96

Figure 53: Pharmaceuticals & Healthcare, Global, Infectious Disease, Number of Deals and Deal Value (US$ m), 2015 – 2019 100

Figure 54: Pharmaceuticals & Healthcare, Global, Infectious Disease, Number of Deals and Deal Value (US$ m), Q1 2019-Q4 2019 102

Figure 55: Pharmaceuticals & Healthcare, Global, Immunology, Number of Deals and Deal Values (US$ m), 2015 – 2019 106

Figure 56: Pharmaceuticals & Healthcare, Global, Immunology, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 108

Figure 57: Pharmaceuticals & Healthcare, Global, Cardiovascular, Number of Deals and Deal Values (US$ m), 2015 – 2019 111

Figure 58: Pharmaceuticals & Healthcare, Global, Cardiovascular, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 113

Figure 59: Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Number of Deals and Deal Values (US$ m), 2015 – 2019 116

Figure 60: Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 118

Figure 61: Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), 2015 – 2019 121

Figure 62: Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), Q1 2019-Q4 2019 123

Figure 63: Pharmaceuticals & Healthcare, North America, Number of Deals and Deal Value (US$ m), 2015 – 2019 126

Figure 64: Pharmaceuticals & Healthcare, North America, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 128

Figure 65: Pharmaceuticals & Healthcare, Europe, Number of Deals and Deal Value (US$ m), 2015 – 2019 132

Figure 66: Pharmaceuticals & Healthcare, Europe, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 134

Figure 67: Pharmaceuticals & Healthcare, Asia-Pacific, Number of Deals and Deal Value (US$ m), 2015 – 2019 138

Figure 68: Pharmaceuticals & Healthcare, Asia-Pacific Region, Deals, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 140

Figure 69: Pharmaceuticals & Healthcare, Rest of the World Deals, Number of Deals and Deal Value (US$ m), 2015 – 2019 143

Figure 70: Pharmaceuticals & Healthcare, Rest of the World Deals, Number of Deals and Deal Value (US$ m), Q1 2019–Q4 2019 146

Figure 71: Pharmaceuticals & Healthcare, Global, Top Financial Advisors, M&A, Number of Deals and Deal Value (US$ m), 2019 149

Figure 72: Pharmaceuticals & Healthcare, Global, Top Financial Advisors, Equity Offerings, Number of Deals and Deal Value (US$ m), 2019 151

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