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Cartilage Repair Pipeline Report including Stages of Development, Segments, Region and Countries, Regulatory Path and Key Companies, 2022 Update

Cartilage Repair procedures aim to regenerate, restore or replace articular cartilage to reduce joint pain and to prevent the development of arthritis. GlobalData's Medical Devices sector report, “Cartilage Repair Pipeline Report including Stages of Development, Segments, Region and Countries, Regulatory Path and Key Companies, 2022 Update" provides comprehensive information about the Cartilage Repair pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress.

The Cartilage Repair report provides key information and data related to:

Extensive coverage of the Cartilage Repair under development

Review details of major pipeline products which include product description, licensing and collaboration details and other developmental activities including pipeline territories, regulatory paths, and estimated approval dates

Reviews of major players involved in the pipeline product development.

Provides key clinical trial data related to ongoing clinical trials such as trial phase, trial status, trial start and end dates, and the number of trials of the major Cartilage Repair pipeline products.

Review of Recent Developments in the segment / industry

The Cartilage Repair report enables you to:

Access significant competitor information, analysis, and insights to improve your R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter strategies to gain competitive advantage

Identify and understand important and diverse types of Cartilage Repair under development

Formulate market-entry and market expansion strategies

Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

The GlobalData Differentiation

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

The data and analysis within this report are driven by GlobalData Medical Intelligence Center (GDMIC) database. GDMIC gives you the key information required to drive sales, investment and deal-making activity in your business. It includes the following:

• 15,000+ data tables showing market size across more than 780 medical equipment segments and 39 countries, from 2015 and forecast to 2025

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• 28,000+ pipeline product profiles

• 56,400+ marketed product profiles

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Contact us to discuss the areas of your business where you need external input, and we will work with you to identify the strongest way forward to meet your needs.

Scope

– Extensive coverage of the Cartilage Repair under development

– The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

– The report reviews the major players involved in the development of Cartilage Repair and list all their pipeline projects

– The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

– The report provides key clinical trial data of ongoing trials specific to pipeline products

– Recent developments in the segment / industry

Reasons to Buy

The report enables you to:

– Formulate significant competitor information, analysis, and insights to improve R&D strategies

– Identify emerging players with potentially strong product portfolio and create effective counter strategies to gain competitive advantage

– Identify and understand important and diverse types of Cartilage Repair under development

– Develop market-entry and market expansion strategies

– Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

– In-depth analysis of the product’s current stage of development, territory and estimated launch date

Key Players

Acro Biomedical Co Ltd

Aesculap Biologics LLC

Askel Healthcare Ltd

Biomimedica, Inc.

Cartilage Inc

CoreSpine Technologies LLC

Department of Biomedical Engineering Columbia University

Forsagen LLC

Gunze Ltd

Hainan Susheng Biological Technology Co Ltd

Histogen Inc

Hy2Care BV

Hyalex Orthopaedics Inc

Isto Biologics

Kytogenics Pharmaceuticals Inc

Lamina Therapeutics

Nanochon LLC

Novatex Bioengineering SA

Olympus RMS Co Ltd

Regentis Biomaterials Ltd

Rosivo Inc

Royal College of Surgeons Ireland

Ruilin Biomedical Nanjing Co Ltd

Sparta Biomedical Inc

Stemmatters Biotecnologia e Medicina Regenerativa SA

Tetratherix Pty Ltd

University of Alberta

University of Oulu

University of Pennsylvania

Table of Contents

1 Table of Contents

2 Introduction 9

2.1 Cartilage Repair Overview 9

3 Products under Development 10

3.1 Cartilage Repair – Pipeline Products by Stage of Development 10

3.2 Cartilage Repair – Pipeline Products by Segment 11

3.3 Cartilage Repair – Pipeline Products by Territory 12

3.4 Cartilage Repair – Pipeline Products by Regulatory Path 13

3.5 Cartilage Repair – Pipeline Products by Estimated Approval Date 14

3.6 Cartilage Repair – Ongoing Clinical Trials 15

4 Cartilage Repair – Pipeline Products under Development by Companies 16

4.1 Cartilage Repair Companies – Pipeline Products by Stage of Development 16

4.2 Cartilage Repair – Pipeline Products by Stage of Development 18

5 Cartilage Repair Companies and Product Overview 20

5.1 Acro Biomedical Co Ltd Company Overview 20

5.1.1 Acro Biomedical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 20

5.2 Aesculap Biologics LLC Company Overview 21

5.2.1 Aesculap Biologics LLC Pipeline Products & Ongoing Clinical Trials Overview 21

5.3 Askel Healthcare Ltd Company Overview 27

5.3.1 Askel Healthcare Ltd Pipeline Products & Ongoing Clinical Trials Overview 27

5.4 Biomimedica, Inc. Company Overview 28

5.4.1 Biomimedica, Inc. Pipeline Products & Ongoing Clinical Trials Overview 28

5.5 Cartilage Inc Company Overview 29

5.5.1 Cartilage Inc Pipeline Products & Ongoing Clinical Trials Overview 29

5.6 CoreSpine Technologies LLC Company Overview 30

5.6.1 CoreSpine Technologies LLC Pipeline Products & Ongoing Clinical Trials Overview 30

5.7 Department of Biomedical Engineering Columbia University Company Overview 31

5.7.1 Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 31

5.8 Forsagen LLC Company Overview 32

5.8.1 Forsagen LLC Pipeline Products & Ongoing Clinical Trials Overview 32

5.9 Gunze Ltd Company Overview 33

5.9.1 Gunze Ltd Pipeline Products & Ongoing Clinical Trials Overview 33

5.10 Hainan Susheng Biological Technology Co Ltd Company Overview 36

5.10.1 Hainan Susheng Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 36

5.11 Histogen Inc Company Overview 37

5.11.1 Histogen Inc Pipeline Products & Ongoing Clinical Trials Overview 37

5.12 Hy2Care BV Company Overview 38

5.12.1 Hy2Care BV Pipeline Products & Ongoing Clinical Trials Overview 38

5.13 Hyalex Orthopaedics Inc Company Overview 41

5.13.1 Hyalex Orthopaedics Inc Pipeline Products & Ongoing Clinical Trials Overview 41

5.14 Isto Biologics Company Overview 46

5.14.1 Isto Biologics Pipeline Products & Ongoing Clinical Trials Overview 46

5.15 Kytogenics Pharmaceuticals Inc Company Overview 47

5.15.1 Kytogenics Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 47

5.16 Lamina Therapeutics Company Overview 48

5.16.1 Lamina Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 48

5.17 Nanochon LLC Company Overview 49

5.17.1 Nanochon LLC Pipeline Products & Ongoing Clinical Trials Overview 49

5.18 Novatex Bioengineering SA Company Overview 50

5.18.1 Novatex Bioengineering SA Pipeline Products & Ongoing Clinical Trials Overview 50

5.19 Olympus RMS Co Ltd Company Overview 51

5.19.1 Olympus RMS Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 51

5.20 Regentis Biomaterials Ltd Company Overview 52

5.20.1 Regentis Biomaterials Ltd Pipeline Products & Ongoing Clinical Trials Overview 52

5.21 Rosivo Inc Company Overview 56

5.21.1 Rosivo Inc Pipeline Products & Ongoing Clinical Trials Overview 56

5.22 Royal College of Surgeons Ireland Company Overview 59

5.22.1 Royal College of Surgeons Ireland Pipeline Products & Ongoing Clinical Trials Overview 59

5.23 Ruilin Biomedical Nanjing Co Ltd Company Overview 60

5.23.1 Ruilin Biomedical Nanjing Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 60

5.24 Sparta Biomedical Inc Company Overview 63

5.24.1 Sparta Biomedical Inc Pipeline Products & Ongoing Clinical Trials Overview 63

5.25 Stemmatters Biotecnologia e Medicina Regenerativa SA Company Overview 64

5.25.1 Stemmatters Biotecnologia e Medicina Regenerativa SA Pipeline Products & Ongoing Clinical Trials Overview 64

5.26 Tetratherix Pty Ltd Company Overview 65

5.26.1 Tetratherix Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 65

5.27 University of Alberta Company Overview 66

5.27.1 University of Alberta Pipeline Products & Ongoing Clinical Trials Overview 66

5.28 University of Oulu Company Overview 67

5.28.1 University of Oulu Pipeline Products & Ongoing Clinical Trials Overview 67

5.29 University of Pennsylvania Company Overview 68

5.29.1 University of Pennsylvania Pipeline Products & Ongoing Clinical Trials Overview 68

6 Cartilage Repair- Recent Developments 69

6.1 Jan 10, 2022: Cline receives clearance for ex-vivo testing of StemCART product on human cartilage tissue 69

6.2 Dec 09, 2021: Stopping arthritis before it starts 69

7 Appendix 71

7.1 Methodology 71

7.2 About GlobalData 74

7.3 Contact Us 74

7.4 Disclaimer 74

List of Tables

Cartilage Repair – Pipeline Products by Stage of Development 10

Cartilage Repair – Pipeline Products by Segment 11

Cartilage Repair – Pipeline Products by Territory 12

Cartilage Repair – Pipeline Products by Regulatory Path 13

Cartilage Repair – Pipeline Products by Estimated Approval Date 14

Cartilage Repair – Ongoing Clinical Trials 15

Cartilage Repair Companies – Pipeline Products by Stage of Development 16

Cartilage Repair – Pipeline Products by Stage of Development 18

Acro Biomedical Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 20

ACROCHONDRO – Product Status 20

ACROCHONDRO – Product Description 20

Aesculap Biologics LLC Pipeline Products & Ongoing Clinical Trials Overview 21

Novocart – Ankle – Product Status 21

Novocart – Ankle – Product Description 21

Novocart – Hip – Product Status 22

Novocart – Hip – Product Description 22

Novocart 3D – Product Status 22

Novocart 3D – Product Description 23

Novocart 3D Plus – Product Status 23

Novocart 3D Plus – Product Description 24

Aesculap Biologics LLC – Ongoing Clinical Trials Overview 25

Novocart 3D – A Phase III, Prospective, Randomized, Partially Blinded Multi-center Study to Measure the Safety and Efficacy of NOVOCART 3D Compared to Microfracture in the Treatment of Articular Cartilage Defects 26

Novocart 3D – Safety and Efficacy of NOVOCART 3D in the Treatment of Articular Cartilage Defects Following Failure on Microfracture 26

Askel Healthcare Ltd Pipeline Products & Ongoing Clinical Trials Overview 27

COPLA Scaffold – Product Status 27

COPLA Scaffold – Product Description 27

Biomimedica, Inc. Pipeline Products & Ongoing Clinical Trials Overview 28

GRADION Hip Total Cartilage Replacement (TCR) Device – Product Status 28

GRADION Hip Total Cartilage Replacement (TCR) Device – Product Description 28

Cartilage Inc Pipeline Products & Ongoing Clinical Trials Overview 29

Hyaleon – Product Status 29

Hyaleon – Product Description 29

CoreSpine Technologies LLC Pipeline Products & Ongoing Clinical Trials Overview 30

Cartilage Removal System – Product Status 30

Cartilage Removal System – Product Description 30

Department of Biomedical Engineering Columbia University Pipeline Products & Ongoing Clinical Trials Overview 31

Echon – Product Status 31

Echon – Product Description 31

Forsagen LLC Pipeline Products & Ongoing Clinical Trials Overview 32

BioAdhesive – Product Status 32

BioAdhesive – Product Description 32

Gunze Ltd Pipeline Products & Ongoing Clinical Trials Overview 33

Meniscal Scaffold – Product Status 33

Meniscal Scaffold – Product Description 33

Gunze Ltd – Ongoing Clinical Trials Overview 34

Meniscal Scaffold – An Exploratory Clinical Study of Gunze’s Biodegradable Scaffold for Meniscal Repair in Patients with Knee Pain 35

Hainan Susheng Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 36

Acellular Cartilage Repair Device – Product Status 36

Acellular Cartilage Repair Device – Product Description 36

Histogen Inc Pipeline Products & Ongoing Clinical Trials Overview 37

HST003 – Product Status 37

HST003 – Product Description 37

Hy2Care BV Pipeline Products & Ongoing Clinical Trials Overview 38

Injectable Plaster – Product Status 38

Injectable Plaster – Product Description 38

Hy2Care BV – Ongoing Clinical Trials Overview 39

Injectable Plaster – A Multi-center, Pivotal, Non-randomized, Prospective, Open-label Study to Evaluate the Safety and Performance of the Hy2Care Injectable Hydrogel for the Repair of Cartilage Defects in the Knee 40

Hyalex Orthopaedics Inc Pipeline Products & Ongoing Clinical Trials Overview 41

Hyalex Cartilage Replacement Implant – Ankle – Product Status 41

Hyalex Cartilage Replacement Implant – Ankle – Product Description 41

Hyalex Cartilage Replacement Implant – Foot – Product Status 42

Hyalex Cartilage Replacement Implant – Foot – Product Description 42

Hyalex Cartilage Replacement Implant – Hand – Product Status 42

Hyalex Cartilage Replacement Implant – Hand – Product Description 43

Hyalex Cartilage Replacement Implant – Hip – Product Status 43

Hyalex Cartilage Replacement Implant – Hip – Product Description 43

Hyalex Cartilage Replacement Implant – Knee – Product Status 44

Hyalex Cartilage Replacement Implant – Knee – Product Description 44

Hyalex Cartilage Replacement Implant – Shoulder – Product Status 44

Hyalex Cartilage Replacement Implant – Shoulder – Product Description 45

Hyalex Cartilage Replacement Implant – Wrist – Product Status 45

Hyalex Cartilage Replacement Implant – Wrist – Product Description 45

Isto Biologics Pipeline Products & Ongoing Clinical Trials Overview 46

RevaFlex – Product Status 46

RevaFlex – Product Description 46

Kytogenics Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 47

MACC-Based Device – Cartilage Repair – Product Status 47

MACC-Based Device – Cartilage Repair – Product Description 47

Lamina Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 48

Lamina.One – Product Status 48

Lamina.One – Product Description 48

Nanochon LLC Pipeline Products & Ongoing Clinical Trials Overview 49

Orthopedic Implant – Cartilage Repair – Product Status 49

Orthopedic Implant – Cartilage Repair – Product Description 49

Novatex Bioengineering SA Pipeline Products & Ongoing Clinical Trials Overview 50

Chondrofill – Product Status 50

Chondrofill – Product Description 50

Olympus RMS Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 51

Cultured Chondrocyte Implantation Kit – Product Status 51

Cultured Chondrocyte Implantation Kit – Product Description 51

Regentis Biomaterials Ltd Pipeline Products & Ongoing Clinical Trials Overview 52

GelrinC – Product Status 52

GelrinC – Product Description 52

GelrinC – Denatured Human Fibrinogen – Product Status 53

GelrinC – Denatured Human Fibrinogen – Product Description 53

Regentis Biomaterials Ltd – Ongoing Clinical Trials Overview 54

GelrinC – Denatured Human Fibrinogen – A Prospective, Open-label, Multicenter Pivotal Study to Evaluate the Safety and Efficacy of GelrinC for the Treatment of Symptomatic Articular Cartilage Defects of the Femoral Condyle: A Comparison to Historical Control Microfracture 55

Rosivo Inc Pipeline Products & Ongoing Clinical Trials Overview 56

Cartesse – Cartilage Repair – Product Status 56

Cartesse – Cartilage Repair – Product Description 56

Cartesse AC – Articular Cartilage Repair – Product Status 57

Cartesse AC – Articular Cartilage Repair – Product Description 57

Cartesse IVD – Intervertebral Disc Repair – Product Status 57

Cartesse IVD – Intervertebral Disc Repair – Product Description 58

Royal College of Surgeons Ireland Pipeline Products & Ongoing Clinical Trials Overview 59

miRNA-Activated Scaffold – Product Status 59

miRNA-Activated Scaffold – Product Description 59

Ruilin Biomedical Nanjing Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 60

Articular Hyaline Cartilage Repair Device – Product Status 60

Articular Hyaline Cartilage Repair Device – Product Description 60

Meniscus Repair Device – Product Status 61

Meniscus Repair Device – Product Description 61

Osteochondral Repair Device – Product Status 61

Osteochondral Repair Device – Product Description 62

Sparta Biomedical Inc Pipeline Products & Ongoing Clinical Trials Overview 63

SBM-01 Biomimetic Implant – Product Status 63

SBM-01 Biomimetic Implant – Product Description 63

Stemmatters Biotecnologia e Medicina Regenerativa SA Pipeline Products & Ongoing Clinical Trials Overview 64

STM-148B – Product Status 64

STM-148B – Product Description 64

Tetratherix Pty Ltd Pipeline Products & Ongoing Clinical Trials Overview 65

Tetraflex – Product Status 65

Tetraflex – Product Description 65

University of Alberta Pipeline Products & Ongoing Clinical Trials Overview 66

3-D Printed Cartilage – Nose – Product Status 66

3-D Printed Cartilage – Nose – Product Description 66

University of Oulu Pipeline Products & Ongoing Clinical Trials Overview 67

Smart 3D Matrices – Chondral Repair – Product Status 67

Smart 3D Matrices – Chondral Repair – Product Description 67

University of Pennsylvania Pipeline Products & Ongoing Clinical Trials Overview 68

Injectable Polymer – Cartilage Repair – Product Status 68

Injectable Polymer – Cartilage Repair – Product Description 68

Glossary 73

List of Figures

Cartilage Repair – Pipeline Products by Stage of Development 10

Cartilage Repair – Pipeline Products by Segment 11

Cartilage Repair – Pipeline Products by Territory 12

Cartilage Repair – Pipeline Products by Regulatory Path 13

Cartilage Repair – Pipeline Products by Estimated Approval Date 14

Cartilage Repair – Ongoing Clinical Trials 15

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